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GenomicsEffect of Ets1 knockdown in the P5424 thymic cell line
We performed ChIP-Seq for Ets1 and histone modifications in P5424 thymic cells, without and with Ets1 knockdown via shRNA. Overall, we find that loss of Ets1 results in specific, higher occupancy of H3K4me1-marked nucleosomes at the Ets1 binding site, but not H3K4me3 nucleosomes. We verified the spe...
ORGANISM(S): Mus musculus 
2015-12-19 | E-GEOD-74042 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of Ets1-/- CD4+ CD8+ thymocytes
We performed ChIP-Seq for hallmark TFs (Ets1, Runx1), histone modification marks (H3K4me1, H3K4me2, H3K4me3, H3K27me3, H3K36me3), total RNA Pol II, short RNA-Seq as well as nucleosome mapping mainly in murine Rag2 -/- thymocytes. We also performed ChIP-Seq for E47 as well as nucleosome mapping, gene...
ORGANISM(S): Mus musculus 
2015-12-19 | E-GEOD-73849 | biostudies-arrayexpress
TranscriptomicsETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq)
ETS1 and RAS/ERK regulate a common gene expression program in establishing enviroment suitable for prostate cancer cell migration. mRNA profiles of luciferase knockdown (WT), ETS1 knockdown, and U0126 treated DU145 cells were generated using deep sequencing, in triplicate, using Illumina HiSeq. Knoc...
ORGANISM(S): Homo sapiens 
2014-10-07 | E-GEOD-59020 | biostudies-arrayexpress
GenomicsExpression Data from Ets1/2 WT, Ets1KO, Ets2KO and Ets1/2 DKO endothelial cells
Expression Data from Ets1/2 WT, Ets1KO, Ets2KO and Ets1/2 DKO endothelial cells
PRJNA588437 | ENA
GenomicsUpregulation of TFH profile in absence of Ets1 expression
Upregulation of TFH profile in absence of Ets1 expression
PRJNA434077 | ENA
GenomicsEWSR1::FLI1 fusion oncoproteins’ regulation of ETS1 (RNA-seq)
EWSR1::FLI1 fusion oncoproteins’ regulation of ETS1 (RNA-seq)
PRJNA1017518 | ENA
TranscriptomicsChip-chip from Mouse E11.5 distal limb tissue cells for Gabpa, Ets1, Elf1, Etv4, Etv5 antibody
Two different groups of Ets transcription factors differentially act directly at the ZRS to define the spatial expression of Shh in the limb. Chromatin immunoprecipitation (ChIP) of Gabpa, Ets1, Etv4, Etv5 and Elf1 and by ChIP-on-chip analysis demonstrated that with the exception of Elf1 all bind d...
ORGANISM(S): Mus musculus 
2012-02-01 | E-GEOD-33997 | biostudies-arrayexpress
GenomicsFunction of Ets1 in regulating macrophage polarization and adipose inflammation
Function of Ets1 in regulating macrophage polarization and adipose inflammation
PRJNA1129453 | ENA
GenomicsEWSR1::FLI1 fusion oncoproteins’ regulation of ETS1 (ChIP-seq)
EWSR1::FLI1 fusion oncoproteins’ regulation of ETS1 (ChIP-seq)
PRJNA1016476 | ENA
GenomicsEWSR1::FLI1 fusion oncoproteins’ regulation of ETS1 (RNA-seq)
EWSR1::FLI1 fusion oncoproteins’ regulation of ETS1 (RNA-seq)
PRJNA1017354 | ENA
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