Sort   by:  
 Page size 
ProteomicsEukaryotic Initiation factor 4B is a multi-functional RNA binding protein that regulates histone mRNAs
In diffuse large B-cell lymphoma (DLBCL) poor outcome is associated with EIF4B-dependent stimulation of the DEAD box helicase eIF4A that unwinds RNA structures in 5’ untranslated regions (UTRs) in mRNAs that encode proteins with a role in cell proliferation. We carried out iCLIP to examine differenc...
ORGANISM(S): Homo sapiens (Human) 
2024-09-04 | PXD042538 | Pride
Eukaryotic initiation factor 4b (eif4b)  mrna translational control  histone mrnas  rna turnover 
UnknownControl of cell survival and proliferation by mammalian eukaryotic initiation factor 4B.
Not available
S-EPMC2832492 | biostudies-literature
UnknownYeast eukaryotic initiation factor 4B (eIF4B) enhances complex assembly between eIF4A and eIF4G in vivo.
Not available
S-EPMC3554905 | biostudies-literature
GenomicsBinding to the Ribosome by Eukaryotic Initiation Factor 4B Drives Yeast Translational Control in Response to Urea
Binding to the Ribosome by Eukaryotic Initiation Factor 4B Drives Yeast Translational Control in Response to Urea
PRJNA578373 | ENA
UnknownEukaryotic initiation factor 4B is a multi-functional RNA binding protein that regulates histone mRNAs.
Not available
S-EPMC11514447 | biostudies-literature
TranscriptomicsBinding to the Ribosome by Eukaryotic Initiation Factor 4B Drives Yeast Translational Control in Response to Urea
The yeast eukaryotic initiation factor 4B binds the 40S subunit in translation preinitiation complexes (PICs) and promotes mRNA binding. Here we have compared the effects of disrupting eIF4B RNA- and ribosome-binding domains under ~1400 growth conditions. The RNA-binding RRM was dispensable for stre...
ORGANISM(S): Saccharomyces cerevisiae 
2020-04-15 | GSE139097 | GEO
GenomicsEukaryotic Initiation factor 4B is a multi-functional RNA binding protein that regulates histone mRNAs
Eukaryotic Initiation factor 4B is a multi-functional RNA binding protein that regulates histone mRNAs
PRJNA979168 | ENA
UnknownA role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma.
Not available
S-EPMC4017261 | biostudies-literature
TranscriptomicsMicroarray expression data of A375 eIF4B-knockout (KO; KO/LacZ) and eIF4B-rescued (KO/eIF4B) cells with or without vemurafenib treatment
Activating Transcription Factor 4 (ATF4) is a key transcription factor of the integrated stress response, which assists cells to survive in response to tumor microenvironmental and therapeutic stresses. BRAF inhibitors, such as vemurafenib, are also known to induce ATF4 in BRAF-mutated melanoma cell...
ORGANISM(S): Homo sapiens 
2021-08-13 | GSE179452 | GEO
GenomicsMicroarray expression data of A375 eIF4B-knockout (KO KO/LacZ) and eIF4B-rescued (KO/eIF4B) cells with or without vemurafenib treatment
Microarray expression data of A375 eIF4B-knockout (KO KO/LacZ) and eIF4B-rescued (KO/eIF4B) cells with or without vemurafenib treatment
PRJNA743872 | ENA
Sort   by:  
 Page size