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MetabolomicsAn ambient-temperature storage and stabilization device performs comparably to flash-frozen collection for stool metabolomics in infants

BACKGROUND: Stool metabolites provide essential insights into the function of the gut microbiome. The current gold standard for storage of stool samples for metabolomics is flash-freezing at - 80 °C which can be inconvenient and expensive. Ambient temperature storage of stool is ...

2021-01-27 | MTBLS201 | MetaboLights
MetabolomicsOxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers
Resistance to endocrine treatments and CDK4/6 inhibitors is considered a near-inevitability in most patients with estrogen receptor positive breast cancers (ER + BC). By genomic and metabolomics analyses of patients' tumours, metastasis-derived patient-derived xenografts (PDX) and isogenic cell line...
2023-06-27 | MTBLS3342 | MetaboLights
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S-EPMC5455766 | biostudies-literature
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S-EPMC6241746 | biostudies-literature
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S-EPMC5098601 | biostudies-literature
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S-EPMC6962055 | biostudies-literature
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S-EPMC10755839 | biostudies-literature
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S-EPMC9469914 | biostudies-literature
UnknownGermline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas.
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S-EPMC3785128 | biostudies-literature
UnknownAlcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium.
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S-EPMC7611162 | biostudies-literature
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