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TranscriptomicsVitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy
The poor clinical outcome in pancreatic ductal adenocarcinoma (PDA) has been attributed to intrinsic resistance to chemotherapy and a growth-permissive tumor microenvironment. Quiescent pancreatic stellate cells (PSCs) are neuroendocrine, nestin-positive, lipid-accumulating cells whose homologues i...
ORGANISM(S): Mus musculus 
2014-10-03 | E-GEOD-43770 | biostudies-arrayexpress
UnknownHexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) alters maternal and fetal glucose and lipid metabolism and produces neonatal mortality, low birthweight, and hepatomegaly in the Sprague-Dawley rat.
Not available
S-EPMC7775906 | biostudies-literature
UnknownDevelopmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) and perfluorooctane sulfonate (PFOS).
Not available
S-EPMC8821375 | biostudies-literature
TranscriptomicsTranscriptomics of environmental adaptation and survival in wild adult Pacific Sockeye Salmon (Oncorhynchus nerka) during spawning migration
a salmonid microarray was used to characterize environmentally-regulated shifts in gene expression between ocean and river habitats in gill and liver tissues of wild migrating adult Pacific sockeye salmon (Oncorhynchus nerka). To correlate gene expression with survival, non-lethal biopsy sampling of...
ORGANISM(S): Oncorhynchus nerka 
2011-06-12 | E-GEOD-22346 | biostudies-arrayexpress
UnknownDose additive maternal and offspring effects of oral maternal exposure to a mixture of three PFAS (HFPO-DA, NBP2, PFOS) during pregnancy in the Sprague-Dawley rat.
Not available
S-EPMC10681034 | biostudies-literature
ProteomicsELF3-AP MS at ZT4 in wt, phyb and phya mutant backgrounds
Molecular basis of flowering under natural long-day conditions in Arabidopsis
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-09-25 | PXD010518 | Pride
Ap-ms Arabidopsis Early flowering3 Plants 
UnknownPractice Patterns of Pulse Dose Corticosteroid Use for Patients Hospitalized With Acute Exacerbations of Idiopathic Pulmonary Fibrosis in the United States.
Not available
S-EPMC12646616 | biostudies-literature
TranscriptomicsEmergence of a developmental stage-dependent human liver disease signature demonstrated by directed differentiation of alpha-1 antitrypsin deficient iPS cells [HumanMethylation450]
We monitored 9 pluripotent stem cell lines across three time points of hepatic directed differentiation, representing 3 developmental stages: undifferentiated (T0), definitive endoderm (T5), and early hepatocyte (T24). ESCs (n=3) and patient-derived normal (n=3) or PiZZ (n=3) iPSCs were analyzed in ...
ORGANISM(S): Homo sapiens 
2015-04-15 | E-GEOD-66077 | biostudies-arrayexpress
UnknownCumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat.
Not available
S-EPMC9944680 | biostudies-literature
ProteomicsDissecting the molecular diversity and commonality of bovine and human treponemes identifies key survival and adhesion mechanisms
Here, we report the first complete genomes of three cultivable treponeme species from bovine digital dermatitis (DD) skin lesions, two comparative human treponemes and a bovine gastrointestinal (GI) isolate. Key genomic differences between bovine and human treponemes implicate microbial mechanisms t...
ORGANISM(S): Treponema sp. T19 Treponema pedis Treponema ruminis Treponema phagedenis Treponema medium Treponema sp. T320A 
2021-03-16 | PXD022419 | Pride
Bovine digital dermatitis Treponemes Shotgun lc msms 
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