Sort   by:  
 Page size 
TranscriptomicsChanges in gene expression in the retina of diabetic Long Evans rats after one, four, and twelve weeks of diabetes
Purpose. Patients with diabetic retinopathy may experience severe vision loss due to macular edema and neovascularization secondary to vascular abnormalities. However, before these abnormalities become apparent, there are functional deficits in contrast sensitivity, color perception, and dark adapta...
ORGANISM(S): Rattus norvegicus 
2011-10-31 | E-GEOD-28831 | biostudies-arrayexpress
TranscriptomicsMicro-RNAs in Adult Long-Evans (Turku/AB) Rat Liver are Refractory to 96 Hours Dioxin Treatment
Dioxin-like chemicals are well-known for their ability to upregulate expression of numerous genes via the AH receptor (AHR). However, recent transcriptomic analyses in several laboratories indicate that dioxin-like chemicals or AHR genotype itself also can downregulate levels of mRNAs encoded by nu...
ORGANISM(S): Rattus norvegicus 
2007-08-14 | E-GEOD-8469 | biostudies-arrayexpress
TranscriptomicsExpression data from the basolateral amygdala of Long-Evans rats with a history of limited intermittent sucrose snacks
To study the molecular mediators of naturally rewarding effects of palatable food we used a model of palatable “snacking” (Ulrich-Lai et al., 2007) in which rats are given chronic, brief access to a limited amount of sucrose solution (30%). Single housed, male Long-Evans rats (250g) (n=12 per...
ORGANISM(S): Rattus norvegicus 
2010-02-21 | E-GEOD-20344 | biostudies-arrayexpress
TranscriptomicsTargets of the transcription factor Brachyury in differentiating mouse ES cells
Brachyury (or T) is expressed in the primitive streak, tailbud and notochord of the early mouse embryo (Herrmann et al., 1990; Wilkinson et al., 1990). It plays a key role in early development: mouse embryos lacking functional Brachyury protein fail to gastrulate properly, do not form a differentiat...
ORGANISM(S): Mus musculus 
2012-05-28 | E-GEOD-16646 | biostudies-arrayexpress
TranscriptomicsNanoString analysis of a rat liver mRNA panel following TCDD treatment
Profiling of mRNA abundances with high-throughput platforms such as microarrays and RNA-Seq has become an important tool in both basic and biomedical research. However these platforms remain prone to systematic errors, and have challenges in clinical and industrial application. As a result it is sta...
ORGANISM(S): Rattus norvegicus 
2013-12-31 | E-GEOD-43251 | biostudies-arrayexpress
TranscriptomicsMicroRNAs in adult rodent liver and response to dioxin
This SuperSeries is composed of the following subset Series: GSE8467: Micro-RNAs in Adult Rat Liver are Refractory to 19 Hours Dioxin Exposure GSE8468: Micro-RNAs levels in wildtype vs. Ahr-null adult mouse liver constitutively and in response to doxin treatment. GSE8469: Micro-RNAs in Adult Long-E...
ORGANISM(S): Mus musculus 
2007-08-14 | E-GEOD-8474 | biostudies-arrayexpress
UnknownMechanical switching and coupling between two dissociation pathways in a P-selectin adhesion bond.
Not available
S-EPMC509195 | biostudies-literature
TranscriptomicsGermline genomic variations associated with childhood acute lymphoblastic leukemia
We identified germline single nucleotide polymorphisms (SNPs) associated with childhood acute lymphoblastic leukemia (ALL) and its subtypes. Using the Affymetrix 500K Mapping array and publicly available genotypes, we identified 18 SNPs whose allele frequency differed (P<1x10-5) between a pediatric...
ORGANISM(S): Homo sapiens 
2009-08-16 | E-GEOD-17195 | biostudies-arrayexpress
TranscriptomicsEffects of pregnancy and progesterone supplementation on endometrial gene expression in cattle
An increase in circulating progesterone (P4) concentrations is associated with increased pregnancy success in beef and dairy cattle. Our objective was to ascertain differential effects of elevated P4 concentrations following conception on endometrial gene expression in beef heifers on Days 5, 7, 13 ...
ORGANISM(S): Bos taurus 
2011-10-17 | E-GEOD-33030 | biostudies-arrayexpress
TranscriptomicsRNA-seq profiling of the bovine cervix at 6 timepoints during the peri-oestrus period.
The estrous cycles of Limousin heifers (n = 30) were synchronized by insertion of a controlled internal drug release (CIDR) device (1.94 g progesterone; Pfizer Animal Health) placed into the vagina for 8 days. A 0.5 mg intramuscular injection of a prostaglandin F2α (PG) analogue (PG, Estrumate, Sher...
ORGANISM(S): Bos taurus 
2013-01-04 | E-GEOD-38225 | biostudies-arrayexpress
Sort   by:  
 Page size