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MetabolomicsCharacterization of Whole Blood EVs Using PRotein Organic Solvent PRecipitation

Blood plays a vital role in diagnostic medicine by providing essential information for assessing health and diagnosing various conditions. Routine blood tests can reveal important biomarkers that support early diagnosis and timely intervention. Recently, extracellular vesicles (EVs) have emerged ...

2026-08-24 | MTBLS12801 | MetaboLights
MetabolomicsThe untargeted metabolites of field EVs from Xinglinwan Reservoir, Xiamen, China.

Microorganisms secrete extracellular vesicles (EVs) that transport bioactive molecules such as proteins, metabolites, and enzymes. While their functions are well studied in model microbes, their ecological contributions to natural ecosystems remain largely unexplored.To address this issue, we per...

2026-01-21 | MTBLS12874 | MetaboLights
MetabolomicsBacteria regulate aging physiology in microalgae via induced vesicle production and the methionine cycle (Metabolomics profiling of FACS purified EVs)

In annually reoccurring patterns, microalgae form blooms that persist and decline thereby contributing massively to global biogeochemical cycles. The decline of blooms is mainly caused by nutrient limitation and goes ahead with the aging of individual algal cells. Nutrient intake can re-initiate ...

2024-05-07 | MTBLS5401 | MetaboLights
TranscriptomicsDifferentially enriched miRNAs in EVs derived from young and aged osteocytes of mice
Vascular calcification often occurs with osteoporosis, a contradictory association called “calcification paradox”. We find that extracellular vesicles (EVs) released from aged bone matrix (AB-EVs) during bone resorption favor adipogenesis rather than osteogenesis of BMSCs and augment calcification o...
ORGANISM(S): Mus musculus 
2022-02-15 | E-MTAB-11417 | biostudies-arrayexpress
TranscriptomicsCrosstalk between the effects of extracellular vesicles (Evs) and TNF on U937 human monocyte cell line
Under physiological conditions, extracellular vesicles (EVs) are present simultaneously in the extracellular compartment together with cytokines. Thus, we hypothesized that EVs in combination with cytokines induce different responses of monocyte cells compared to EVs or cytokines alone. Human monocy...
ORGANISM(S): Homo sapiens 
2013-06-19 | E-GEOD-47897 | biostudies-arrayexpress
TranscriptomicsComparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles containing specific repertoires of genetic material. In mammals, EVs can mediate the horizontal transfer of various cargos and signaling molecules, notably miRNA and mRNA species. Whether this form of intercellular communication prevai...
ORGANISM(S): Homo sapiens 
2016-06-15 | E-GEOD-76173 | biostudies-arrayexpress
ProteomicsIsolation and Characterisation of EVs from Feline Plasma: A Comparative Analysis with Human Plasma Derived EVs
Extracellular vesicles (EVs) are nanoparticles found in all biological fluids, capable of transporting biological material around the body. Extensive research into the physiological role of EVs has led to the development of the Minimal Information for Studies of Extracellular Vesicles (MISEV) framew...
ORGANISM(S): Homo sapiens (Human) 
2022-07-13 | PXD034369 | Pride
Human Extracellular vesicles Cat Bruker timstof pro 
TranscriptomicsNanoString assays of miRNA in MCF7 and MCF10A cells and in extracellular vesicles (EVs) derived from these cells.
The goal of this study is to identify unique miRNA profiles of EVs from MCF7 and MCF10A cells that distinguish their cellular origin. 654 human mature miRNAs were analyzed in NanoString assays to identify miRNA with high abundance in MCF7 EVs and the greatest fold change for MCF7 EVs relative to MCF...
ORGANISM(S): Homo sapiens 
2015-02-21 | E-GEOD-66165 | biostudies-arrayexpress
Transcriptomicstranscriptional profile of islet EVs for diabetes genes
Identification of transcriptional profile of several genes involved in diabetes in islet-derived extracellular vesicles (Evs). Recently, EVs are identified as a new mechanism in cell-to-cell communication by transfer of protein and genic information (mRNA, microRNA). Their role is under investigatio...
ORGANISM(S): Homo sapiens 
2012-08-02 | E-MEXP-3695 | biostudies-arrayexpress
GenomicsEVs MSC miRNA-seq
EVs MSC miRNA-seq
PRJNA745950 | ENA
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