Excitability - OmicsDI

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Organisms

Mus musculus (188)
Homo sapiens (59)
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Danio rerio (5)
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Caenorhabditis elegans (2)
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mouse gut metagenome (1)

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Instrument Platform

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UNIPROT ID/AC

O43526 (1)
O88944 (1)
P29992 (1)
P32241 (1)
P16220 (1)
Q49AN0 (1)
P56645 (1)
O15055 (1)
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O00327 (1)
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CHEBI ID

CHEBI:16865 (3)
CHEBI:22660 (3)
CHEBI:22653 (3)
CHEBI:24898 (3)
CHEBI:16811 (3)
CHEBI:17802 (3)
CHEBI:17568 (3)
CHEBI:16828 (3)
CHEBI:17351 (3)
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CHEBI:5235 (1)
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CHEBI:9175 (1)
CHEBI:16749 (1)
CHEBI:17996 (1)
CHEBI:17526 (1)
CHEBI:29103 (1)
CHEBI:18420 (1)
CHEBI:25107 (1)
CHEBI:16595 (1)
CHEBI:29108 (1)
CHEBI:15996 (1)
CHEBI:17552 (1)
CHEBI:33699 (1)
CHEBI:15422 (1)

Metabolite Name

L-Glutathione oxidized (2)
PI 38:4 (2)
Nicotinamide adenine dinucleotide phosphate (NADP+) (1)
Beta-Nicotinamide adenine dinucleotide reduced (NADH) (1)
Beta-Nicotinamide adenine dinucleotide (NAD+) (1)
Adenosine 5'-triphosphate (5'-ATP) (1)
Inosine 5'-monophosphate (5'-IMP) (1)
Ketoleucine (4-Methyl-2-oxopentanoic acid) (1)
SM 9:1;2O/18:5 (1)
PC 17:1_18:1 (1)
2-(1H-benzimidazol-2-yl)-3-(1,3-benzodioxol-5-yl)acrylonitrile (1)
PS 3:0_16:0 (1)
QMH (1)
DG 17:0_18:2 (1)
PC 19:2_20:4 (1)
SM 38:3;3O (1)
PC 32:4_28:6 (1)
PC 22:4_22:4 (1)
LPC 40:10 (1)
PS 18:1_20:5 (1)
SHexCer 20:1;2O/17:0 (1)
PS 44:12 (1)
DGCC 42:6_44:12 (1)
TG 18:5_26:7_30:8 (1)
PC 18:0_19:1 (1)
LPC 30:0 (1)
PE O-26:7_18:4 (1)
LPE 40:7 (1)
LPC 19:1-SN2 (1)
LPC 44:12 (1)

First Public Date

2026 (77)
2025 (70)
2024 (46)
2014 (27)
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2019 (24)
2022 (21)
2021 (19)
2020 (18)
2018 (12)
2015 (8)
2017 (6)
2016 (4)
2013 (2)

Modelling Approach

Ordinary differential equation model (10)

Lab affiliation

CECAD Excellence Center, University of Cologne, Germany, D-50931 Center for Physiology and Pathophysiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany, D-50931 (4)
Department of Cell Biology, Harvard Medical School, Boston MA 02115 (2)
CECAD Excellence Center & Center for Physiology, Medical Faculty, University of Cologne, Germany (2)
IRCCS Istituto G Gaslini (2)
Institute of Cellular Neurosciences II University of Bonn, Germany (1)
Inserm UNIS UMR_S 1072 51 Boulevard Pierre Dramard 13015 Marseille FRANCE (1)
Lab of Systems Neuroscience, Institute for Neuroscience, Department of Health Science and Technology, Swiss Federal Institute of Technology ETH, 8057 Zurich, Switzerland (1)
Department of Life Sciences, University of Bath, UK (1)
Department of Biochemistry and Molecular Biology, Center for Mechanical Excitability, Institute for Biophysical Dynamics, Prizker School for Molecular Engineering, The University of Chicago, Chicago, Illinois, USA (1)
Proteomic Platform Necker, INSERM US24, SFR Necker Université de Paris (1)
Structural & Molecular Biology, UCL London, UK (1)
UCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland (1)
Institute of Pharmacology Center for Physiology and Pharmacology Medical University of Vienna, Austria (1)
The department of Molecular and cellular neurobiology, Neuroproteomics, CNCR, Vrije University Amsterdam (1)
Department of Neuroscience, Washington Univeristy in St. Louis, USA (1)
Department of Neurology, Yale School of Medicine, Yale University, new haven CT, USA (1)
Motor Neuron Disease Research Centre, Macquarie University, NSW, 2113, Australia (1)
Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), 50931 Cologne, Germany. (1)
Tufts University School of Medicine (1)
Laboratory of Cell Biophysics Nencki Institute of Experimental Biology PAS Warsaw, Poland (1)
Deparetmento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. (1)
Washington University in St. Louis, School of Medicine, Department of Cell Biology and Physiology,Center for Investigation of Membrane Excitability Diseases (1)
Department of Fundamental Neurosciences (DNF) University of Lausanne Rue du Bugnon 9 CH-1005 Lausanne Switzerland (1)
Department of Anatomy & Neurobiology University of Tennessee Health Science Center (1)
The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK (1)
Institute for Immunology, University Medical Center of the Johannes Gutenberg-University Mainz, Germany (1)
School of Life Sciences and Technology, Tongji University, Shanghai, China (1)
European Institute of Oncology (1)
Medical University of South Carolina, Department of Neuroscience, Charleston, SC, USA (1)
Department of Internal Medicine, Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, United States (1)

IsPrivate

False (10)

Model Flag

Non Kinetic (1)

Study type

Transcription profiling by array (37)
RNA-seq of coding RNA (11)
ChIP-seq (3)
RNA-seq of total RNA (2)
RNA-seq of non coding RNA (2)
Transcription profiling by SAGE (1)
Animal - High-throughput sequencing (1)
CLIP-seq (1)
Methylation profiling by array (1)

Release Date

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2012 (129)
2011 (127)
2013 (122)
2010 (103)
2026 (81)
2009 (77)
2008 (70)
2007 (33)
2004 (27)
2005 (23)
2006 (21)
2003 (13)
2000 (9)
2002 (6)
2001 (6)
1999 (4)
1998 (3)
1997 (3)

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Large neutral amino acid levels tune perinatal neuronal excitability and survival

Surprisingly little is known about the critical metabolic changes that neural cells have to undergo during development and how even mild, temporary shifts in this program can influence brain circuitries and behavior. Inspired by the discovery that mutations in SLC7A5, a transporter of metabolically-...

2023-03-28 | MTBLS6578 | MetaboLights

RNA-seq of NEAT1 knockdown in neuronal excitability

PRJEB9006 | ENA

Modeling K,ATP--dependent excitability in pancreatic islets.

Not available

S-EPMC4223185 | biostudies-literature

Downregulation of calcium-activated potassium channels drives cortical excitability dysfunction in a model of Itgb3-associated autism

Layer V pyramidal neurons, particularly pyramidal tract (PT) neurons, are essential for cortical output. Genetic studies have linked ITGB3, the gene encoding the cell-adhesion molecule β3 integrin, to autism spectrum disorder (ASD), yet its role in brain function remains poorly understood. Here, we ...

ORGANISM(S): Mus musculus (Mouse)

2025-10-13 | PXD056477 | Pride