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TranscriptomicsMicroRNA profiling of brain metastasis competent cell-derived exosomes
Objective of this work was to characterize the miRNA profile of exosomes isolated from brain-homing cell lines (MDA-MB-231BR, CTC1BMSM, and 70W) with their respective parental non-brain metastatic cell lines (MDA-MB-231P, CTC1P and MeWo). Exosomes derived from the six cell lines were isolated. Brain...
ORGANISM(S): Homo sapiens 
2013-07-16 | E-GEOD-48934 | biostudies-arrayexpress
TranscriptomicsExosomes mediate protective messages during oxidative stress; role of exosomal shuttle RNA
Exosomes are small extracellular nano-vesicles of endocytic origin that mediate different signals between cells, by surface interactions and by shuttling of functional RNA from one cell to another. In this study, we show that exosomes, produced by mouse mast cells exposed to oxidative stress, change...
ORGANISM(S): Mus musculus 
2011-01-07 | E-GEOD-24886 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiles of immune cells and their exosomes
Microarray analysis of exosomal miRNAs vs the miRNAs of their respective donor cells. To determine the miRNA repertoires of exosomes secreted by immune cells, we isolated exosomes from cell supernatants of the Raji B cell line, the Jurkat-derived J77 T cell line, and primary dendritic cells (DCs) de...
ORGANISM(S): Homo sapiens 
2011-03-17 | E-GEOD-27997 | biostudies-arrayexpress
TranscriptomicsmRNA profiles of activated and resting T cells and their exosomes
Microarray analysis of exosomal and cellular mRNAs in activated and resting primary human T lymphoblasts Primary human T lymphoblasts were obtained from eight donors and total RNA was isolated from cells and derived exosomes before and after activation with PMA plus ionomycin.
ORGANISM(S): Homo sapiens 
2014-02-27 | E-GEOD-50971 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiles of activated and resting T cells and their exosomes
Microarray analysis of exosomal and cellular miRNAs in activated and resting primary human T lymphoblasts Primary human T lymphoblasts were obtained from eight donors and total RNA was isolated from cells and derived exosomes before and after activation with PMA plus ionomycin.
ORGANISM(S): Homo sapiens 
2014-02-27 | E-GEOD-50953 | biostudies-arrayexpress
TranscriptomicsExosomes isolated from M.tb infected cells modulate macrophage response to IFN-gamma
we studied the role of exosomes isolated from M.tb infected macrophages in modulating the macrophage response to IFN-γ. Nimblegen microarray gene expression studies were used to compare the suppression of IFN-γ inducible genes by exosomes relative to the virulent strain of M.tuberculosis. Overall ou...
ORGANISM(S): Mus musculus 
2011-06-05 | E-GEOD-29731 | biostudies-arrayexpress
MetabolomicsMetabonomics of Chlorella exosomes

We extracted Chlorella vulgaris exosomes by ultraionization method, and analyzed its active substances by non targeted metabonomics detection.

2025-11-21 | MTBLS13365 | MetaboLights
TranscriptomicsNext generation sequencing of small RNAs isolated from exosomes in human semen
Preparation of exosomes isolated from semen contain a substantial amount of RNA, mostly from 20 to 100 nucleotides in length. We sequenced separately 20-40 and 40-100 nucleotide fractions of RNA from exosomes isolated from semenal fluid from six healthy donors. We found various classes of small non...
ORGANISM(S): Homo sapiens 
2014-06-04 | E-GEOD-56076 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of rhabdomyosarcoma-derived exosomes compared to donor cells, using the Affymetrix GeneChip miRNA 3.0 array
Exosomes were isolated by differential centrifugation from the fusion negative human embryonal rhabdomyosarcoma (ERMS) cell lines (JR1, Rh36, and RD) and fusion positive alveolar RMS (ARMS) cell lines (Rh30 and Rh41) and characterized by western blot for exosomal markers. miRNA content of the RMS-de...
ORGANISM(S): Homo sapiens 
2016-12-01 | E-MTAB-5321 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression analysis of the effects of a parasitic nematode's secreted exosomes on mammalian cells.
We show that a gastrointestinal nematode that infects mice, Heligmosomoides polygyrus, secretes vesicles packaged with specific microRNAs (miRNAs) and Y RNAs as well as a nematode-specific Argonaute protein. The vesicles are of intestinal origin and are enriched for homologs of mammalian proteins fo...
ORGANISM(S): Mus musculus 
2014-12-24 | E-GEOD-55941 | biostudies-arrayexpress
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