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MetabolomicsMining for natural product antileishmanials in a fungal extract library
Leishmaniasis is a Neglected Tropical Disease caused by the insect-vector borne protozoan parasite, Leishmania species. Infection affects millions of the World’s poorest, however vaccines are absent and drug therapy limited. Recently, public-private partnerships have developed to identify new modes ...
2021-02-12 | MTBLS868 | MetaboLights
ProteomicsSWATH mass spectrometry performance using extended ion assay libraries
The use of data-independent acquisition methods such as SWATH for mass spectrometry based proteomics is usually performed using peptide MS/MS reference ion assay libraries which enable identification and quantitation of peptide peak areas. Reference assay libraries can be generated locally through ...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2016-05-12 | PXD002836 | Pride
Extended library Dia Swath 
TranscriptomicsRNA sequencing of 968xY0036 fission yeast recombinant library
We generated the first recombinant strain library for fission yeast and conducted an RNA-seq based QTL study of the coding, non-coding, and antisense transcriptomes. We cross the lab strain 968 with the lab strain Y0036 to generate segregant. We used RNA-seq for both expression profiling and gentoyp...
ORGANISM(S): Schizosaccharomyces pombe 
2014-12-04 | E-MTAB-2640 | biostudies-arrayexpress
UnknownShifting temporal patterns in physical usage of a health sciences library following the extension of operational hours.
Not available
S-EPMC11486077 | biostudies-literature
ProteomicsProsit: Proteome-wide prediction of peptide tandem mass spectra by deep learning
In this study, we extended the ProteomeTools peptide library (PROPEL, see PXD004732 and PXD010595) to train a deep neural network resulting in chromatographic retention time and fragment ion intensity predictions for (tryptic) peptides that exceed the quality of the experimental data.
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) Escherichia Coli (ncbitaxon:562) Saccharomyces Cerevisiae (ncbitaxon:4932) Homo Sapiens (ncbitaxon:9606) Caenorhabditis Elegans (ncbitaxon:6239) 
2021-03-12 | MSV000087047 | MassIVE
TranscriptomicsExtended self-renewal and accelerated reprogramming in the absence of Kdm5b
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-10-14 | E-GEOD-46893 | biostudies-arrayexpress
TranscriptomicsExtended Primate aCGH
This set includes individuals from 10 different primate species whose genomic DNA was used in an array-based comparative genomic hybridization (aCGH)using human cDNA microarrays to detect gene copy number variation across 10 primate species. An organism part comparison experiment design type compare...
ORGANISM(S): Callithrix sp. 
2012-02-24 | E-GEOD-9028 | biostudies-arrayexpress
TranscriptomicsMethod Study
High-throughput sequencing (HTS) of antibody amplicon libraries has become a powerful method in the emerging field of systems immunology. However, numerous sources of bias in HTS workflows may affect antibody repertoire data. A crucial step in antibody amplicon library preparation is the addition of...
ORGANISM(S): Mus musculus 
2014-02-20 | E-MTAB-2226 | biostudies-arrayexpress
GenomicsEpigenetic and metabolic remodeling during the acquisition of extended pluripotency
Epigenetic and metabolic remodeling during the acquisition of extended pluripotency
PRJNA564808 | ENA
GenomicsSequencing-based ssDNA detection
Meiotic DNA double stranded breaks (DSBs) initiate genetic recombination in discrete areas of the genome called recombination hotspots. Although DSBs can be directly mapped using ChIP-Seq and antibody against ssDNA-associated proteins, genome-wide mapping of recombination hotspots in mammals is stil...
ORGANISM(S): Mus musculus 
2012-02-21 | E-GEOD-34592 | biostudies-arrayexpress
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