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Extraintestinal pathogenic Escherichia coli (ExPEC) have a capacity to cause serious infections of blood, the central nervous system and particularly the urinary tract. Relatively little is known about how ExPEC adapt their cell-wide protein expression to environments with different carbon sources a...
ORGANISM(S): Escherichia coli 
2016-07-04 | PXD002912 | Pride
PhoP is considered a regulator of virulence despite being conserved in both pathogenic and non-pathogenic Enterobacteriaceae. While Escherichia coli strains represent both non-pathogenic commensal isolates and numerous virulent pathotypes, the PhoP virulence regulator has only been studied in comme...
ORGANISM(S): Escherichia coli CFT073 
Avian pathogenic Escherichia coli strains frequently cause extra-intestinal infections and are responsible for significant economic losses in the poultry industry worldwide. APEC isolates are closely related to human extraintestinal pathogenic E.coli strains and may also act as pathogens for humans....
ORGANISM(S): Escherichia coli 
Genome sequencing of extraintestinal pathogenic Escherichia coli
In this study the transcriptional response of an ExPEC E. coli strain (CFT073) to human serum was investigated. In response, CFT073 up-regulated expression of iron and manganese acquisition systems and induced expression of iron regulated genes. High osmolarity of serum induced the osmotic shock res...
ORGANISM(S): Escherichia coli 
Escherichia coli is an important human pathogen, among others a cause of severe diarrhea diseases and urinary tract infections. The ability to distinguish different pathogenic E. coli subspecies is crucial for correct treatment of the infection. Characterization and quantification of clinical isolat...
ORGANISM(S): Escherichia coli 
2020-10-19 | PXD005760 | Pride
Unconventional Extraintestinal Pathogenic Escherichia coli Genome sequencing and assembly
Extraintestinal pathogenic Escherichia coli (ExPEC) is a common bacterial strain causing diverse diseases in humans and animals. To analyse the detailed mechanisms underlying ExPEC-mediated sepsis in humans, the transcriptome response of mice at 3h,6h, and 12h after ExPEC infection was analyzed by R...
ORGANISM(S): Mus musculus 
2022-11-11 | GSE140637 | GEO
In Escherichia coli, the highly conserved enzymes MiaA and MiaB mediate the sequential prenylation and methylthiolation of adenosine-37 within tRNAs that decode UNN codons. We found that MiaA, but not MiaB, is critical to the fitness and virulence of extraintestinal pathogenic E. coli (ExPEC), a maj...
ORGANISM(S): Escherichia coli 
2022-02-14 | PXD024782 | Pride
Chemoreceptors enable bacteria to modulate their swimming behavior in accordance with the perceived environmental cues. Bacteria exhibit large diversity of stimuli sensed by their chemoreceptors, whereas the output of receptors to the chemotaxis signaling pathway that controls flagellar motor is typ...
ORGANISM(S): Escherichia coli 
2025-06-13 | PXD064677 | Pride
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