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TranscriptomicsGene expression changes in testes from Abcg8 knockout mice compared to wild-type mice or to Abcg8 knockout mice where plant sterol entry was blocked by ezetimibe
Abcg8 knockout mice, fed chow, are infertile. These mice also are susceptible to absorption and retention of xenosterols contained in the diet. Ezetimibe, a blocker of dieary sterol entry, can reverse the fertility in Abcg8 knockout mice. In order to identify if the xenosterols resulted in disruptio...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-39813 | biostudies-arrayexpress
GenomicsEzetimibe Ameliorates Ankylosing Spondylitis by Suppressing Th17 Differentiation
Ezetimibe Ameliorates Ankylosing Spondylitis by Suppressing Th17 Differentiation
PRJNA847949 | ENA
GenomicsRNA-seq of Snu-449 cells treated with Ezetimibe or control
RNA-seq of Snu-449 cells treated with Ezetimibe or control
PRJNA938039 | ENA
GenomicsEffect of ezetimibe treatment on gene expression of TGFβ1-activated primary human lung fibroblasts
Effect of ezetimibe treatment on gene expression of TGFβ1-activated primary human lung fibroblasts
PRJNA938140 | ENA
TranscriptomicsEffect of ezetimibe treatment on gene expression of TGFβ1-activated primary human lung fibroblasts
To verify whether ezetimibe inhibits myofibroblast differentiation at the transcriptome level and to reveal the mechanism of action of ezetimibe, we sequenced primary human lung fibroblasts that we isolated and cultured.
ORGANISM(S): Homo sapiens 
2024-02-22 | GSE225982 | GEO
GenomicsThe NTCP receptor inhibitor Ezetimibe reduces the toxicity of α-amanitin: in vitro and in vivo study.
The NTCP receptor inhibitor Ezetimibe reduces the toxicity of α-amanitin: in vitro and in vivo study.
PRJNA987536 | ENA
UnknownEffects of combined ezetimibe and simvastatin therapy as compared with simvastatin alone in patients with type 2 diabetes: a prospective randomized double-blind clinical trial.
Not available
S-EPMC2928341 | biostudies-literature
TranscriptomicsEzetimibe Ameliorates Ankylosing Spondylitis by Suppressing Th17 Differentiation
Oxidized low-density lipoprotein influences the Th17/Treg balance. A high serum concentration of oxidized low-density lipoprotein is negatively correlated with the number of Treg cells and positively correlated with the number of Th17 cells. Therefore, we expected that the reduction of blood lipid l...
ORGANISM(S): Mus musculus 
2022-06-11 | GSE205850 | GEO
TranscriptomicsTransintestinal cholesterol transport is important in mice and humans and controls ezetimibe induced fecal neutral sterol excretion
Except for conversion to bile salts, there is no major cholesterol degradation pathway in mammals. Efficient excretion from the body is therefore a crucial element in cholesterol homeostasis. Yet, the existence and importance of these pathways in humans is a matter of debate. We quantified cholester...
ORGANISM(S): Mus musculus 
2016-11-04 | GSE77236 | GEO
TranscriptomicsSystems biology analysis unravels complementary action of combined Rosuvastatin and Ezetimibe therapy
Transcriptomics analysis to understand both efficacy and side effects of a cholesterol lowering drug combination therapy based on biological pathways and molecular processes affected by each drug alone or in combination. We have treated ApoE*3Leiden mice, a humanized atherosclerosis model with a uni...
ORGANISM(S): Mus musculus 
2013-02-27 | E-GEOD-38688 | biostudies-arrayexpress
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