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TranscriptomicsWhole genome analysis regulation in HepG2 cells exposed to cadmium
Cadmium (Cd) is a metal present in working and living environments known to be toxic and carcinogenic, but its mechanism of action remains still unclear. We investigated the gene expression modulation in human hepatoma cell line HepG2 after exposure to 2 M-BM-5m and 10 M-BM-5m cadmium using Agilent...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-31286 | biostudies-arrayexpress
TranscriptomicsHey3Met2 human ovarian cancer cells overexpressing wild type or catalytically-dead mutant RNASET2
Hey3Met2 cells were stably transfected with plasmids encoding either wild-type RNASET2 or a catalytically dead form (whose cDNA has been previously mutagenized in the two CAS catalytic sites) or with the empty vector as a control. The control of ovarian tumorigenesis by RNASET2 occurs through modifi...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-28478 | biostudies-arrayexpress
UnknownObserver-Agent Kinematic Similarity Facilitates Action Intention Decoding.
Not available
S-EPMC7018748 | biostudies-literature
TranscriptomicsRNASET2-silenced and control OVCAR3 cell clones injected into nude mice.
To investigate the molecular pathways underlying RNASET2-mediated tumor suppression in vivo, we investigated the gene expression profile of tumor samples obtained from control and RNASET2-silenced OVCAR3 xenografts, respectively. In order to evaluate the contribution of human cancer cells and the...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-43029 | biostudies-arrayexpress
TranscriptomicsSILENCING OF PNPLA6, THE NEUROPATHY TARGET ESTERASE (NTE) CODIFYING GENE, ALTERS HUMAN NEURODIFFERENTIATION IN VITRO
Neuropathy Target Esterase (NTE) is a protein involved in the development of a polyneuropathy caused by exposure to certain organophosphorus compounds. In vivo and in vitro studies have also associated NTE with embryonic development since NTE null mice embryos are non-viable, and silencing the NTE-c...
ORGANISM(S): Homo sapiens 
2014-10-06 | E-GEOD-55761 | biostudies-arrayexpress
UnknownThe Proactive Synergy Between Action Observation and Execution in the Acquisition of New Motor Skills.
Not available
S-EPMC8986982 | biostudies-literature
UnknownKicking in or kicking out? The role of the individual motor expertise in predicting the outcome of rugby actions.
Not available
S-EPMC10020490 | biostudies-literature
UnknownObservation of others' actions during limb immobilization prevents the subsequent decay of motor performance.
Not available
S-EPMC8617512 | biostudies-literature
TranscriptomicsUnderstanding toxicity pathways of gold nanoparticles: RNA expression study on Caco-2 human colon carcinoma cells
A safer design and higher eficacy of nano-gold therapeutic formulations requires examination of cellular responses to gold nanoparticles (AuNPs). In this work we compared cellular uptake, cytotoxicity and RNA expression patterns induced in Caco-2 cells of citrate-stabilized Au NP of two different si...
ORGANISM(S): Homo sapiens 
2015-01-22 | E-GEOD-55349 | biostudies-arrayexpress
GenomicsHigh density copy number analysis and whole exome sequencing of chronic lymphocytic leukemia

The pathogenesis of chronic lymphocytic leukemia (CLL), the most common leukemia in adults, is still largely unknown since the full spectrum of genetic lesions that are present in the CLL genome, and therefore the number and identity of dysregulated cellular pathways, have not been iden...

phs000364.v1.p1 | EGA
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