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ProteomicsSite-specific mapping and quantification of protein S-sulphenylation in cells

Jing Yang, Vinayak Gupta, Kate S. Carroll, & Daniel C. Liebler, (2014) Nature Communications 5, 4776, doi:10.1038/ncomms5776

Cysteine S-sulphenylation provides redox regulation of protein f...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084244 | MassIVE
TranscriptomicsExpression data from DC-induced Hopx-deficient and sufficient regulatory T cells after immunization
We found that Hopx is required for the function of DC-induced regulatory T cells in vivo. We used microarrays to identify relevant Hopx-targets in such cells after antigenic re-challenge in vivo. CD25/Foxp3 double positive DC-induced Hopx-deficient and sufficient regulatory T cells were FACS sorted ...
ORGANISM(S): Mus musculus 
2010-08-29 | E-GEOD-23167 | biostudies-arrayexpress
ProteomicsYang: Site-specific mapping and quantification of protein S-sulfenylation in cells
The files in this archive represent the supporting data for "Site-specific mapping and quantification of protein S-sulfenylation in cells," a paper to appear in Nature Communications (2014). The authors are Jing Yang, Vinayak Gupta, Kate S. Carroll, and Daniel C. Liebler, working at Vanderbilt Univ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-07-10 | MSV000078777 | MassIVE
TranscriptomicsEpigenomic comparison of distinct pluripotent stem cell states reveals a new class of enhancers with roles throughout mammalian development (RNA-seq)
NaM-CM-/ve mouse embryonic stem cells (mESCs) and primed epiblast stem cells (mEpiSCs) represent successive snapshots of pluripotency during embryogenesis. Using transcriptomic and epigenomic mapping, we show that a small fraction of transcripts are differentially expressed between mESCs and mEpiSCs...
ORGANISM(S): Mus musculus 
2014-06-04 | E-GEOD-57403 | biostudies-arrayexpress
TranscriptomicsThe gene expression profile of dendritic cells can be used as a predictor of function.
The human lung cancer cell line A549 was cultured in media alone, with cyclophosphamide (CPM), oxaliplatin (OXP) or DMSO alone for 72 hours. The exhausted culture media were aspirated and stored at -20C. Peripheral blood mononuclear cells (PBMCs) were isolated from four pathologically healthy dono...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-MTAB-389 | biostudies-arrayexpress
TranscriptomicsExpression array analysis of the hepatocyte growth factor (HGF) invasive program
HGF stimulates mitogenesis, motogenesis and morphogenesis in most epithelial target cells. Selective inhibition of HGF signaling blocks spontaneous metastasis, but not primary tumor growth, in the prostate adenocarcinoma derived PC3M cell xenograft model. To identify the HGF activated genes and path...
ORGANISM(S): Homo sapiens 
2015-08-25 | E-GEOD-71404 | biostudies-arrayexpress
TranscriptomicsSox4 is a key oncogenic target in C/EBP? mutant Acute Myeloid Leukemia
Mutation or epigenetic silencing of the transcription factor C/EBP? is observed in ~10% of patients with acute myeloid leukemia (AML). In both cases, a common global gene expression profile is observed, but down-stream targets relevant for leukemogenesis are not known. Here we identify Sox4 as a dir...
ORGANISM(S): Mus musculus 
2013-03-23 | E-GEOD-45430 | biostudies-arrayexpress
TranscriptomicsMurine Bone Marrow Stromal Cell Response to Granulocyte Colony-Stimulating Factor
Neutrophil homeostasis is maintained, in part, by the regulated release of neutrophils from the bone marrow. Constitutive expression of the chemokine CXCL12 by bone marrow stromal cells provides a key retention signal for neutrophils in the bone marrow through activation of its receptor CXCR4. Her...
ORGANISM(S): Mus musculus 
2010-07-14 | E-GEOD-22925 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human monocytes from patients with dominant negative mutations in PPARg and rosiglitazone treated cells to investigate PPARg regulated gene expression in human dendritic cells
In order to gain insights into how PPARg regulates different facets of dendritic cell (DC) differentiation, we sought to identify PPARg regulated genes and gene networks in monocyte-derived dendritic cells using global gene expression profiling. We employed an exogenous ligand activation approach us...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8658 | biostudies-arrayexpress
TranscriptomicsDrug-based modulation of endogenous stem cells promotes functional remyelination in vivo
Multiple sclerosis involves an aberrant autoimmune response and progressive failure of remyelination in the central nervous system. Prevention of neural degeneration and subsequent disability requires remyelination through the generation of new oligodendrocytes, but current treatments exclusively ta...
ORGANISM(S): Mus musculus 
2015-04-13 | E-GEOD-63804 | biostudies-arrayexpress
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