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UnknownBcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells.
Not available
S-EPMC3382939 | biostudies-literature
UnknownStructure-guided rational design of α/β-peptide foldamers with high affinity for BCL-2 family prosurvival proteins.
Not available
S-EPMC3970217 | biostudies-literature
UnknownApoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax.
Not available
S-EPMC2577705 | biostudies-literature
UnknownHigh-resolution structural characterization of a helical alpha/beta-peptide foldamer bound to the anti-apoptotic protein Bcl-xL.
Not available
S-EPMC2843084 | biostudies-literature
UnknownStructural basis of Bcl-xL recognition by a BH3-mimetic α/β-peptide generated by sequence-based design.
Not available
S-EPMC3263372 | biostudies-literature
UnknownConformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligands.
Not available
S-EPMC2781605 | biostudies-literature
UnknownATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types.
Not available
S-EPMC5600837 | biostudies-literature
UnknownMutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis.
Not available
S-EPMC3044969 | biostudies-literature
UnknownEvaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain.
Not available
S-EPMC3364022 | biostudies-literature
UnknownBCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer.
Not available
S-EPMC10907349 | biostudies-literature
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