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TranscriptomicsResponse of gastric epithelial progenitors to H. pylori isolates from Swedish patients with chronic atrophic gastritis 2
Helicobacter pylori infection is associated with development of gastric adenocarcinoma in a subset of infected humans, especially those that develop an antecedent condition, chronic atrophic gastritis (ChAG) characterized by loss of acid-producing parietal cells. Studies in a gnotobiotic transgenic ...
ORGANISM(S): Helicobacter pylori 
2010-06-20 | E-GEOD-16439 | biostudies-arrayexpress
TranscriptomicsDissecting the in vivo metabolic potential of two human gut acetogens.
Fermenting microbial communities generate hydrogen: its removal through production of acetate, methane, or hydrogen sulfide modulates the efficiency of energy extraction from available nutrients in many ecosystems. We noted that pathway components for acetogenesis are more abundantly and consistentl...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2010-05-21 | E-GEOD-21906 | biostudies-arrayexpress
MetabolomicsSmall intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders
Small intestinal bacterial overgrowth (SIBO) has been implicated in symptoms associated with functional gastrointestinal disorders (FGIDs), though mechanisms remain poorly defined and treatment involves non-specific antibiotics. Here we show that SIBO based on duodenal aspirate culture reflects an o...
2019-04-30 | MTBLS876 | MetaboLights
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