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TranscriptomicsProbucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice
To discern whether the same transcriptional signature of mitochondrial dysfunction previously reported in B6.Alb/cre,Pdss2loxP/loxP liver-conditional knockout mice (Peng, Falk et al. PLoS Genetics, 2008 [PMID 18437205]) was present regardless of Pdss2 mutation type, as well as to assess whether phar...
ORGANISM(S): Mus musculus 
2011-06-07 | E-GEOD-27954 | biostudies-arrayexpress
TranscriptomicsCross-platform expression microarray performance in a mouse model of mitochondrial disease therapy
Microarray expression profiling has become a valuable tool in the evaluation of the genetic consequences of metabolic disease. Although 3â??-biased gene expression microarray platforms were the first generation to have widespread availability, newer platforms are gradually emerging that have more u...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-18677 | biostudies-arrayexpress
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