Sort   by:  
 Page size 
TranscriptomicsMiRNA expression profiling or ERCC1 deficient and control mouse lineage negative bone marrow cells
MiRNA expression differences induced by ERCC1 deficiency.
ORGANISM(S): Mus musculus 
2015-04-09 | E-MTAB-3298 | biostudies-arrayexpress
TranscriptomicsMiRNA expression profiling or ERCC1 deficient and control mouse lineage negative, ScaI positive, Kit positive (LSK) bone marrow cells
MiRNA expression differences induced by ERCC1 deficiency.
ORGANISM(S): Mus musculus 
2015-04-09 | E-MTAB-3310 | biostudies-arrayexpress
TranscriptomicsHigh-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
The ability to perturb genes in human cells is crucial for elucidating gene function and holds great potential for finding therapeutic targets for diseases such as cancer. To extend the catalog of human core and context- dependent fitness genes, we have developed a high-complexity second-generation ...
ORGANISM(S): Homo sapiens 
2015-11-25 | E-GEOD-75189 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse C2AS12 cells infected with (1) wt p300 + tTA, (2) p300deltaTAZ2 +tTA, (3) wt p300 +tTA +doxycycline to define the transcriptional network regulated by ectopic expression of the transcriptional co-activator protein, p300 and define its role in promoting muscle cell survival
The primary focus of these studies is to define the transcriptional network regulated by ectopic expression of the transcriptional co-activator protein, p300, in order to define its mechanism(s) of action in promoting muscle cell survival. Our laboratory has generated a murine C2-derived myoblast ce...
ORGANISM(S): Mus musculus 
2007-12-07 | E-GEOD-4224 | biostudies-arrayexpress
UnknownThe genomic and immune landscape of long-term survivors of high-grade serous ovarian cancer.
Not available
S-EPMC10478425 | biostudies-literature
TranscriptomicsArginine utilization following mycobacteria infection in macrophages is dependent on autocrine-paracrine signaling
Nitric oxide (NO) produced by macrophages (MØs) is toxic to both host tissues and invading pathogens and its regulation is therefore essential to suppress host cytotoxicity. MØ arginase 1 (Arg1) inhibits NO production by competing with NO synthases for arginine, the common substrate of NO synthases ...
ORGANISM(S): Mus musculus 
2010-07-14 | E-GEOD-22935 | biostudies-arrayexpress
TranscriptomicsPhenotype Enhancement Screen of a Regulatory spx Mutant Unveils a Role for the ytpQ Gene in the Control of Iron Homeostasis.
Spx is a global regulator of genes that are induced by disulfide stress in Bacillus subtilis. Most of the Spx-regulated genes (SRGs) are of unknown function, but many encode products conserved in low %GC Gram positive bacteria. Using a gene-disruption library of B. subtilis genomic mutations, the SR...
ORGANISM(S): Bacillus subtilis 
2011-10-24 | E-GEOD-28872 | biostudies-arrayexpress
TranscriptomicsExpression data from healthy postmenopausal women on 4 different types of hormone therapy, the RET study
Postmenopausal hormone therapy (HT) is associated with many diseases and conditions, but the underlying molecular mechanisms involved are incompletely understood. The aim of the current study was to investigate the effect of 4 types of HT on gene transcription. 24 women (6 women in 4 treatment group...
ORGANISM(S): Homo sapiens 
2012-01-17 | E-GEOD-24859 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling of the porcine developing cortex and cerebellum
MicroRNA expression profiling using microRNA microarrays was performed on the porcine developing brain. Two tissues, cortex and cerebellum, were sampled at each of three different developmental stages: gestation day 50 (F50), gestation day 100 (F100) and three months old (named adult), respectively....
ORGANISM(S): Sus scrofa 
2010-09-14 | E-GEOD-24106 | biostudies-arrayexpress
TranscriptomicsSystematic evaluation of variability in simulated ChIP-chip experiments
The most widely-used method for detecting and measuring genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Many tiling array platforms, amplification methods, and analysis algorithms exist for ChIP-chip, but a rigorous assessment...
ORGANISM(S): Homo sapiens 
2008-01-31 | E-GEOD-9842 | biostudies-arrayexpress
Sort   by:  
 Page size