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TranscriptomicsAltered Hematopoietic Cell Gene Expression Precedes Development of Therapy-Related Myelodysplasia and Identifies Patients at Risk
Therapy-related myelodysplasia or acute myeloid leukemia (t-MDS/AML) is a lethal complication of cancer treatment. Although t-MDS/AML development is associated with known genotoxic exposures, its pathogenesis is not well understood and methods to predict risk of development of t-MDS/AML in individua...
ORGANISM(S): Homo sapiens 
2011-12-12 | E-GEOD-23025 | biostudies-arrayexpress
UnknownChemically modified CRISPR-Cas9 enables targeting of individual G-quadruplex and i-motif structures, revealing ligand-dependent transcriptional perturbation.
Not available
S-EPMC12796454 | biostudies-literature
UnknownChemically modified CRISPR-Cas9 enables targeting of individual G-quadruplex and i-motif structures, revealing ligand-dependent transcriptional perturbation.
Not available
S-EPMC12330486 | biostudies-literature
UnknownEffect of Naringenin on Potassium Bromate-Induced Hepatotoxicity In Vivo: A Dose-Dependent Study.
Not available
S-EPMC12580169 | biostudies-literature
UnknownEffects of thermal conditioning on the performance of Pocillopora acuta adult coral colonies and their offspring.
Not available
S-EPMC8550305 | biostudies-literature
UnknownMicrobiota dysbiosis in honeybee (Apis mellifera L.) larvae infected with brood diseases and foraging bees exposed to agrochemicals.
Not available
S-EPMC7890499 | biostudies-literature
UnknownA Suppressor Mutation Partially Reverts the xantha Trait via Lowered Methylation in the Promoter of Genomes Uncoupled 4 in Rice.
Not available
S-EPMC6688194 | biostudies-literature
TranscriptomicsSmall molecule inhibitors suppress expression of both type III secretion and amylovoran biosynthesis genes in Erwinia amylovora
Microarray analysis of E. amylovora treated with compounds no. 3 and no. 9 identified a total of 588 significantly differentially expressed genes. Among them, 95 and 78 genes were, respectively, induced and suppressed by both compounds as compared to DMSO control. Majority of T3SS genes in E. amylov...
ORGANISM(S): Erwinia amylovora 
2013-12-24 | E-GEOD-45602 | biostudies-arrayexpress
UnknownStructure and Stabilities of Solution and Gas Phase Protein Complexes.
Not available
S-EPMC11622221 | biostudies-literature
UnknownDual small-molecule targeting of procaspase-3 dramatically enhances zymogen activation and anticancer activity.
Not available
S-EPMC3954530 | biostudies-literature
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