Metabolic reprogramming in malignant cells is a hallmark of cancer that relies on augmented glycolytic metabolism to support their growth, invasion and metastasis. However, the impact of global adipose metabolism on tumor growth and the drug development by targeting adipose metabolism remain larg...
The dataset includes two parts: a) Proteomics of mouse heart tissue 14 days after myocardial infarction and long-term exercised mice post-myocardial infarction for 14 days; b) Cardiac proteomics of a model of heart failure with preserved ejection fraction (HFpEF) induced by L-NAME and high-fat diet-...
We investigated the impact of both BMP9 deficiency and replenishment on the pathogenesis of MI in mice. Our results showed an aggravated pathological phenotype of MI in BMP9 knockout (KO) mice, which can be alleviated by replenishment of BMP9. Therefore, we further investigated the mechanism whereby...
