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OBJECTIVE: This study aimed to investigate the plasma metabolic profile of patients with extracranial arteriovenous malformations (AVM).

METHOD: Plasma samples were collected from 32 AVM patients and 30 healthy controls (HC). Ultra-high performance liquid c...

2023-10-30 | MTBLS7753 | MetaboLights
TSN, a small molecular compound, was covalently attached to agarose beads via ketone or OH group. Macrophages-derived cell lysates were incubated with these TSN-conjugated beads and mass spectrometry-based proteomic analysis was performed to identify potential TSN interacting proteins
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD039067 | Pride
Novel modalities such as Proteolysis Targeting Chimera (PROTAC) and RNA interference (RNAi) have the ability to inadvertently alter the abundance of endogenous proteins. Currently available in vitro secondary pharmacology assays, which evaluate off-target binding or activity of small molecules, do ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024312 | Pride
Proteomic sequencing was performed on 5 prostate cancer patient tissues and 5 benign prostatic hyperplasia patient tissues collected from Beijing Tongren Hospital Affiliated to Capital Medical University. Differential genes related to the prognosis of prostate cancer were identified, and enrichment ...
ORGANISM(S): Homo sapiens (Human) 
2026-01-23 | PXD066054 | Pride

The relationship between dyslipidemia and type 2 diabetes mellitus (T2D) has been extensively reported, but the global lipid profiles, especially in the East Asia population, associated with the development of T2D remain to be characterized. Liquid chromatography coupled to tandem mass spectromet...

2017-04-26 | MTBLS352 | MetaboLights
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