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UnknownHepatic DsbA-L protects mice from diet-induced hepatosteatosis and insulin resistance.
Not available
S-EPMC5434661 | biostudies-literature
ProteomicsClinical investigation on nebulized human umbilical cord MSC-derived extracellular vesicles for pulmonary fibrosis treatment
Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are recognized as a promising strategy for cell-free therapy, however, their therapeutic role in pulmonary fibrosis remains unrevealed. Here, we report the safety and efficacy of MSC-EVs from human umbilical cord (hUCMSC-EVs) evaluate...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD063385 | Pride
Extracellular vesicles  pulmonary fibrosis  nebulization delivery  lung function recovery  preclinical and clinical trials 
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
TranscriptomicsIdentification of differentially expressed microRNAs from a male sterile Ponkan mandarin (Citrus reticulata Blanco) and its fertile wild type by small RNA and degradome sequencing
High-throughput small RNA and degradome sequencing were performed to identify a large number of miRNAs and their targets. Differential expression of several miRNAs reveals that miRNA regulatory network was closely linked to gametophyte development and male sterility in Ponkan mandarin. The expressio...
ORGANISM(S): Citrus reticulata 
2014-12-08 | E-GEOD-53389 | biostudies-arrayexpress
UnknownSpatio-temporal breather dynamics in microcomb soliton crystals.
Not available
S-EPMC11393309 | biostudies-literature
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
ProteomicsHoneybee Brain LC-MS/MS - Proteomics Reveals the Molecular Underpinnings of Stronger Learning and Memory in Eastern Compared to Western Beess
Honeybee brain has distHoneybee brain has distinct anatomical and functional regions, knowledge on molecular underpinnings of sub-organ to achieve the distinct neural function and the difference between the eastern and western honeybees are still missing. Here, the proteomes of three sub-organs of e...
ORGANISM(S): Apis mellifera (Honeybee) 
2017-12-04 | PXD007091 | Pride
Honeybee mushroom bodies antennal lobes optical lobes proteome 
UnknownUpregulation of cannabinoid receptor-1 and fibrotic activation of mouse hepatic stellate cells during Schistosoma J. infection: role of NADPH oxidase.
Not available
S-EPMC6739633 | biostudies-literature
UnknownA Nucleus-Targeting WT1 Antagonistic Peptide Encapsulated in Polymeric Nanomicelles Combats Refractory Chronic Myeloid Leukemia.
Not available
S-EPMC10534672 | biostudies-literature
UnknownTargeted degradation of Pin1 by an antagonistic peptide enhances gemcitabine therapy in pancreatic cancer.
Not available
S-EPMC12822731 | biostudies-literature
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