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Faratian2009 - Role of PTEN in Trastuzumab resistance This model is described in the article: Systems biology reveals new strategies for personalizing cancer medicine and confirms the role of PTEN in resistance to trastuzumab. Faratian D, Goltsov A, Lebedeva G, Sorokin A, Mo...
2024-09-02 | BIOMD0000000424 | BioModels
Tamoxifen is the most widely prescribed anti-estrogen treatment for patients with ER-positive breast cancer. However, there is still a need for biomarkers that reliably predict endocrine sensitivity in breast cancers and these may well be expressed in a dynamic manner. In this study we assessed ge...
ORGANISM(S): Homo sapiens 
The objective of this study was to measure copy number alterations in a panel of 15 CRC cell lines and relate them to treatment sensitivity. Assessment of copy number variations in a panel of 15 colorectal cancer cell lines
ORGANISM(S): Homo sapiens 
The purpose of this study was to characterise the effects of trastuzumab and pertuzumab, either as single agents or as combination therapy on gene and protein expression in human ovarian cancer in vivo. Illumina BeadChips were used to profile the transcriptome after four days treatment of SKOV3 tumo...
ORGANISM(S): Homo sapiens 
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