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MetabolomicsBrown-fat-mediated tumour suppression by cold-altered global metabolism

Glucose uptake is essential for cancer glycolysis and is involved in non-shivering thermogenesis of adipose tissues. Most cancers use glycolysis to harness energy for their infinite growth, invasion and metastasis. Activation of thermogenic metabolism in brown adipose tissue (BAT) by cold an...

2022-08-12 | MTBLS4856 | MetaboLights
MetabolomicsMetabolism Disorder Promotes Isoproterenol-induced Myocardial Injury in Mice with High Temperature and High Humidity and High-Fat Diet

Isoproterenol (ISO) provides a simple and non-invasive method for inducing myocardial injury with lower mortality and higher reproducibility. Phlegm-damp syndrome, as known as “Tanshi” in Chinese, is one of Traditional Chinese Medicine (TCM) syndrome differentiation, which plays an important role...

2022-01-10 | MTBLS3886 | MetaboLights
MetabolomicsWlingsan ameliorates high-fat diet-induced lipid metabolism disorder

In this study, a HFD-induced lipid metabolism disorder model was established in C57BL/6 mice in vivo, and a palmitic acid (PA)-induced hepatocyte lipid accumulation model was constructed in HepG2 cells in vitro. Using component identification, network pharmacology, transcriptome sequencing, molec...

2026-08-26 | MTBLS14691 | MetaboLights
MetabolomicsFat Deposition in the Muscle of Female and Male Yak and the Correlation of Yak Meat Quality with Fat

Background:

The study of fat deposition in yaks of different gender plays a positive role in improving the meat quality and breeding of yaks. In this work, the characteristic of fat deposition in male and female yaks, and the regulations of gender difference to fat deposition in yaks were ...
2021-08-04 | MTBLS2737 | MetaboLights
MetabolomicsHuanglianjiedu Decoction ameliorates high-fat diet-induced lipid metabolism disorder
In this study, a HFD-induced lipid metabolism disorder model was established in C57BL/6 mice in vivo, and a palmitic acid (PA)-induced hepatocyte lipid accumulation model was constructed in HepG2 cells in vitro. Using component identification, network pharmacology, transcriptome sequencing, molecula...
2026-08-26 | MTBLS14701 | MetaboLights
MetabolomicsYinchenhao Decoction ameliorates high-fat diet-induced lipid metabolism disorder

In this study, a HFD-induced lipid metabolism disorder model was established in C57BL/6 mice in vivo, and a palmitic acid (PA)-induced hepatocyte lipid accumulation model was constructed in HepG2 cells in vitro. Using component identification, network pharmacology, transcriptome sequencing, molec...

2027-06-26 | MTBLS14689 | MetaboLights
MetabolomicsDietary Cetobacterium somerae LY-01 improves lipid metabolism and intestinal health in largemouth bass (Micropterus salmoides) fed a high-fat diet
Non-targeted metabolomics sequencing was performed on the control group diet (C), the high-fat group diet (H), and the high-fat + Cetobacterium somerae LY-01 (HCS9) diet to investigate their effects on intestinal health.
2026-09-03 | MTBLS15536 | MetaboLights
MetabolomicsSteam-exploded okara ameliorates hepatic lipid metabolism in high-fat diet-induced obese C57BL/6J mice: Evidence from multi-omics characterization

Okara, a byproduct of soybean processing, possesses valuable nutritional and physiological properties. Steam explosion, an efficient physical modification technique, can increase the soluble dietary fiber (SDF) content in okara and potentially amplify its health benefits, such as anti-obesity eff...

2025-10-23 | MTBLS13154 | MetaboLights
TranscriptomicsGlycemic index differences of high-fat diets modulate primarily lipid metabolism in murine adipose tissue
We previously reported that a low versus high glycemic index (GI) diet on a high fat (30% kcal fat) background (LGI and HGI, respectively) significantly retarded adverse health effects in C57BL/6J male mice. The LGI diet enhanced whole body insulin sensitivity and repressed high fat diet-induced bod...
ORGANISM(S): Mus musculus 
2011-09-12 | E-GEOD-26930 | biostudies-arrayexpress
MetabolomicsDiabetic heart adrenergic signaling and metabolism (STZ & Isoproterenol, High Fat)
Not available
ORGANISM(S): Mus musculus 
ST000712 | MetabolomicsWorkbench
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