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Open modification searching (OMS) is a powerful search strategy to identify peptides with any type of modification. OMS works by using a very wide precursor mass window to allow modified spectra to match against their unmodified variants, after which the modification types can be inferred from the c...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2019-12-06 | PXD013641 | Pride
We performed single cell RNAseq to measure gene expression in different subsets of lung dendritic cells hyperglycaemic mice. We used streptozotocin model to achieve hyperglycaemia. Each sample contains cells from 4 different mice and hashing was done to allow disentangling which cell comes from whic...
ORGANISM(S): Mus musculus 
8-10 week old wildtype and Cela1-/- in C57BL6 background were treated with 2 units of tracheal porcine pancreatic elastase or PBS and on day 21 lungs were collected, flow sorted, and libraries created from lung cells of 3 mice per group using 10X Chromium controller and cellplex lipid hashing oligos...
ORGANISM(S): Mus musculus 
These samples are part of a study aimed at understanding B lymphopoiesis in the human bone marrow throughout the lifespan and guiding in vitro B lymphopoiesis. This dataset contains transcriptomic data from prenatal and adult bone marrow samples, as well as in vitro experiments, together with the co...
ORGANISM(S): Homo sapiens 
Gene expression and T cell receptor profiles from single cells from populations of T cells stimulated with islet autoantigenic peptides. CD4 T cells were stimulated with native (proinsulin, GAD fragments) or neo-antigen epitopes or flu vaccine (Pediacel). Activated cells (identified as CD19- CD3+ C...
ORGANISM(S): Homo sapiens 
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