We aimed to clarify the metabolomic properties of mice with haploinsufficiency in the autism spectrum disorder-related gene lysine methyltransferase 2c (Kmt2c) (Kmt2c+/fs mice). We collected feces from control (Kmt2c+/+) and Kmt2c+/fs mice, and compared the composition of metabolites using LC-MS ...
Background
This study aimed to obtain a holistic view of remission in pediatric Crohn’s Disease (CD) by integrating six omics datasets from three anatomical compartments.
Methods
Patients with fecal calprotectin below 250 mg/kg were c...
Hepatic fibrosis decreased feces bile acid level. Hepatic fibrosis increased serum bile acid. This result showed that hepatic fibrosis inhibited the excretion of bile acid in clinical patients. This result provided phenotype for hepatic fibrosis patients. Bile acid was important indexes for liver...