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UnknownCD49d is the strongest flow cytometry-based predictor of overall survival in chronic lymphocytic leukemia.
Not available
S-EPMC4876311 | biostudies-literature
TranscriptomicsChanges in gene expression induced by CDK9 inhibition alone and in combination with fludarabine
Using a transcriptomics approach we explored the mechanism(s) of synergy observed between CDKI-73 and fludarabine in primary CLL cells. The cytotoxic effects of CDKI-73 were associated with transcriptional inhibition of cdk9 target genes including MCL1 and XIAP. In contrast, fludarabine induced the ...
ORGANISM(S): Homo sapiens 
2013-06-25 | E-GEOD-48258 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of CD38+ and CD38- cells derived from the same CLL patient reveals distinct gene expression signatures despite their monoclonal origin.
CD38 expression is an important prognostic marker in CLL with high levels of CD38 associated with shorter overall survival. In this study, we used gene expression profiling and protein analysis of highly purified cell-sorted CD38+ and CD38- chronic lymphocytic leukemia cells to elucidate a molecular...
ORGANISM(S): Homo sapiens 
2007-11-11 | E-GEOD-6321 | biostudies-arrayexpress
UnknownEvaluation of an electronic clinical decision support algorithm to improve primary care management of acute febrile illness in rural Cambodia: protocol for a cluster-randomised trial.
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S-EPMC11492946 | biostudies-literature
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