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ProteomicsSSc biomarkers detection in the secretome of TGF1-activated primary human lung fibroblasts.
TGFβ1 is a profibrotic mediator that contributes to a broad spectrum of pathologies, including pulmonary fibrosis (PF). However, the secretome of TGFβ1-stimulated primary human normal lung (NL) fibroblasts has not been well characterized. Using fluorescent 2-dimensional gel electrophoresis (2D-PAGE)...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD023862 | Pride
Tgfbeta Fibroblasts Secretome 
TranscriptomicsLung tissues in systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension
Objective: Pulmonary complications in systemic sclerosis (SSc), including pulmonary fibrosis (PF) and pulmonary arterial hypertension (PAH), are the leading cause of mortality. We compared the molecular fingerprint of SSc lung tissues and matching primary lung fibroblasts to those of normal donors, ...
ORGANISM(S): Homo sapiens 
2013-06-21 | E-GEOD-48149 | biostudies-arrayexpress
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