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TranscriptomicsComparative Pathogenesis of Three Human and Zoonotic SARS-CoV Strains in Cynomolgus Macaques
The severe acute respiratory syndrome (SARS) epidemic was characterized by increased pathogenicity in the elderly due to an early exacerbated innate host response. SARS-CoV is a zoonotic pathogen that entered the human population through an intermediate host like the palm civet. To prevent future in...
ORGANISM(S): Macaca mulatta 
2011-08-31 | E-GEOD-23955 | biostudies-arrayexpress
TranscriptomicsZEBOV-induced changes in macrophage gene expression
Zaire ebolavirus (ZEBOV) infections are associated with high lethality in primates. ZEBOV primarily targets mononuclear phagocytes, which are activated upon infection and secrete mediators believed to trigger initial stages of pathogenesis. The characterization of the responses of target cells to ZE...
ORGANISM(S): Homo sapiens 
2011-08-31 | E-GEOD-31747 | biostudies-arrayexpress
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