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UnknownInhibition of γ-Secretase Leads to an Increase in Presenilin-1.
Not available
S-EPMC5948247 | biostudies-literature
MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
UnknownSupporting dataset on the validation and verification of the analytical method for the biomonitoring of 360 toxicologically relevant pollutants in whole blood.
Not available
S-EPMC7339027 | biostudies-literature
UnknownNutritional Evaluation and Risk Assessment of the Exposure to Essential and Toxic Elements in Dogs and Cats through the Consumption of Pelleted Dry Food: How Important Is the Quality of the Feed?
Not available
S-EPMC8227297 | biostudies-literature
UnknownDisturbed Glucose Metabolism in Rat Neurons Exposed to Cerebrospinal Fluid Obtained from Multiple Sclerosis Subjects.
Not available
S-EPMC5789332 | biostudies-literature
TranscriptomicsTranscriptional profile Lactobacillus plantarum WCFS1 : p-coumaric acid (p-CA) treated cells
Whole genome transcriptional profiling was used to characterize the response of Lactobacillus plantarum WCFS1 human isolate during challenge with p-coumaric acid (p-CA). Twelve independent experiments were performed and mixed at random in groups of four for total of three RNA samples. The transcript...
ORGANISM(S): Lactobacillus plantarum 
2013-01-16 | E-GEOD-40126 | biostudies-arrayexpress
ProteomicsThe pterocarpan (+)-PTC mimics microtubule-destabilizing agents by modulating cytoskeletal proteins in metastatic castration-resistant prostate cancer: a proteomic perspective
Treatment of metastatic castration-resistant prostate cancer (mCRPC) remains clinically challenging due to tumor heterogeneity and drug resistance. Microtubule-targeting agents are a mainstay of mCRPC therapy, but limitations persist regarding progression-free survival. Pterocarpans have emerged as ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD073655 | Pride
Prostate cancer Proteomics Cytoskeleton proteins Pterocarpans Microtubule-targeting agents 
MetabolomicsConformational gating mechanism for processive catalysis of beta(1,3) -glucans

Processive catalysis is a fundamental molecular mechanism in nature to both build and dismantle complex biological polymers such as nucleic acids, proteins and carbohydrates, underpinning a broad spectrum of biotechnological applications. Here, we uncover a processive mechanism for the breakdown ...

2026-03-02 | MTBLS13959 | MetaboLights
UnknownChromosomal polymorphism in the Sporothrix schenckii complex.
Not available
S-EPMC3900657 | biostudies-literature
TranscriptomicsExpression data from arabidopsis root in response to boron toxicity
Boron is an essential micronutrient for plants and is taken up in the form of boric acid (BA). Despite this, a high BA concentration is toxic for the plants, inhibiting root growth and is thus a significant problem in semi-arid areas in the world. In this work, we report the molecular basis for the ...
ORGANISM(S): Arabidopsis thaliana 
2011-11-01 | E-GEOD-32659 | biostudies-arrayexpress
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