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TranscriptomicsSuppression of antitumor immunity by the oncometabolite 2-hydroxyglutarate
Isocitrate dehydrogenase (IDH) mutations, a hallmark of gliomagenesis, result in the production of the oncometabolite R-2-hydroxyglutarate (R-2-HG) which is thought to promote tumorigenesis via DNA methylation. Here we identify an additional immunosuppressive activity of R-2-HG: Tumor cell-derived R...
ORGANISM(S): Homo sapiens 
2016-07-27 | E-GEOD-84849 | biostudies-arrayexpress
TranscriptomicsRNA-seq comparing transcriptome of lymphoblastic cells from FAME patients and control individuals
RNAseq was performed for 10 individuals: three affected individuals (CSDN4, CSDN5, CSDN6) and one healthy spouse (CSDN7) from Family 1, three affected individuals (CSDN1, CSDN2, CSDN3) from Family 5 and three healthy controls (CSDN8, CSDN9, CSDN10).
ORGANISM(S): Homo sapiens 
2019-09-16 | E-MTAB-8301 | biostudies-arrayexpress
Transcriptomicssmall RNA-seq comparing transcriptome (small RNAs) of lymphoblastic cells from FAME patients and control individuals
RNAseq was performed for 10 individuals: three affected individuals (CSDN14, CSDN15, CSDN16) and one healthy spouse (CSDN17) from Family 1, three affected individuals (CSDN11, CSDN12, CSDN13) from Family 5 and three healthy controls (CSDN18, CSDN19, CSDN20).
ORGANISM(S): Homo sapiens 
2019-09-16 | E-MTAB-8300 | biostudies-arrayexpress
UnknownMinimal manifestation status and prednisone withdrawal in the MGTX trial.
Not available
S-EPMC7455358 | biostudies-literature
UnknownEfficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 : A Randomized Controlled Trial.
Not available
S-EPMC9384272 | biostudies-literature
UnknownThe Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19.
Not available
S-EPMC9447373 | biostudies-literature
UnknownEarly trajectories of virological and immunological biomarkers and clinical outcomes in patients admitted to hospital for COVID-19: an international, prospective cohort study.
Not available
S-EPMC11181148 | biostudies-literature
UnknownViral and Host Factors Are Associated With Mortality in Hospitalized Patients With COVID-19.
Not available
S-EPMC11175705 | biostudies-literature
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