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ProteomicsInterferon Regulatory Factors: IRF1 and IRF7 directly regulate gene expression in bats in response to viral infection.
Bat cells and tissue have elevated basal expression levels of antiviral genes commonly associated with IFNα signalling. Here we show IRF1,3 and 7 levels are elevated in most bat tissues and that basally, IRFs contribute to the expression of type I IFN ligands and high expression of Interferon Regula...
ORGANISM(S): Cellular Organisms 
2020-10-23 | PXD021982 | JPOST Repository
UnknownA Glycolipid Adjuvant, 7DW8-5, Enhances the Protective Immune Response to the Current Split Influenza Vaccine in Mice.
Not available
S-EPMC6759631 | biostudies-literature
TranscriptomicsGene expression profiling of wild type and CNS2-deficient Treg cells in the resting state
Resting regulatory T cells (CD4+GFP+CD44lowCD62Lhigh) were sorted from the littermates of male Foxp3gfp and Foxp3ΔCNS2-gfp mice. Poly(A)-tailed RNA were amplified and sequenced on an Ion Torrent platform. RNA-seq of WT and CNS2KO regulatory T cells in the resting state
ORGANISM(S): Mus musculus 
2014-08-14 | E-GEOD-58905 | biostudies-arrayexpress
TranscriptomicsWhite-Opaque Switching in Natural MTLa/alpha Isolates of Candida albicans: Evolutionary Implications for Roles in Host Adaptation, Pathogenesis and Sex
The discovery of white-opaque switching in natural MTLa/alpha isolates of Candida albicans sheds new light on the evolution of phenotypic plasticity and host adaptation. Comparing gene expression of white and opaque cells of a MTL a/alpha strain
ORGANISM(S): Candida albicans 
2013-04-01 | E-GEOD-43938 | biostudies-arrayexpress
TranscriptomicsMechanistic and structural insight into the functional dichotomy between interleukin-2 and interleukin-15
Interleukin-15 (IL-15) and IL-2 possess distinct immunological functions despite both signaling through IL-2Rβ and the common cytokine receptor γ-chain, γc, We find that in the IL-15/IL-15Rα/IL-2Rβ/γc quaternary complex structure, IL-15 heterodimerizes IL-2Rβ and γc identically to the IL-2/IL-2Rα/IL...
ORGANISM(S): Mus musculus 
2012-11-01 | E-GEOD-40350 | biostudies-arrayexpress
TranscriptomicsRobust enumeration of cell subsets from tissue expression profiles (BeadChip)
We introduce CIBERSORT, a method for characterizing cell composition of complex tissues from their gene expression profiles. When applied to enumeration of hematopoietic subsets in RNA mixtures from fresh, frozen, and fixed tissues, including solid tumors, CIBERSORT outperformed other methods with r...
ORGANISM(S): Homo sapiens 
2015-03-29 | E-GEOD-65133 | biostudies-arrayexpress
TranscriptomicsRobust enumeration of cell subsets from tissue expression profiles (HGU133A)
We introduce CIBERSORT, a method for characterizing cell composition of complex tissues from their gene expression profiles. When applied to enumeration of hematopoietic subsets in RNA mixtures from fresh, frozen, and fixed tissues, including solid tumors, CIBERSORT outperformed other methods with r...
ORGANISM(S): Homo sapiens 
2015-03-29 | E-GEOD-65134 | biostudies-arrayexpress
TranscriptomicsRobust enumeration of cell subsets from tissue expression profiles (HGU133Plus2)
We introduce CIBERSORT, a method for characterizing cell composition of complex tissues from their gene expression profiles. When applied to enumeration of hematopoietic subsets in RNA mixtures from fresh, frozen, and fixed tissues, including solid tumors, CIBERSORT outperformed other methods with r...
ORGANISM(S): Homo sapiens 
2015-03-29 | E-GEOD-65135 | biostudies-arrayexpress
UnknownThe Canadian Lung Outcomes in Users of Vaping Devices (CLOUD) Study: protocol for a prospective, observational cohort study.
Not available
S-EPMC11887296 | biostudies-literature
ProteomicsTime-Dependent Proteome Study: Human ovarian cancer tumor samples (0, 5, 30, 60 min)

The objective of the Time-Dependent Proteome Study, was to evaluate changes in the proteome and phosphoproteome when there is a delay in freezing tissues following sample (tumor) excision. The biospecimens used are from patient-derived ovarian cancer tumors.

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-11-05 | MSV000083107 | MassIVE
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