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MetabolomicsContributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer

BACKGROUND Increasing evidence implicates microbiome involvement in the development and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of gut or oral microbiota can lead to colonization in the pancreas, resulting in dysbiosis that culminates ...

2023-08-09 | MTBLS7260 | MetaboLights
TranscriptomicsTranscription profiling of mouse Atm-/-,mTerc-/-,p53-/- triple knock out lymphoma vs. normal mouse DNA (GPL2884)
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7600 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of human GBM tumor vs. normal human DNA induced in mice
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7602 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization (CGH) of human melanoma vs. normal human samples
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7606 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human colon tumor vs normal DNA
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7604 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Atm-/-,mTerc-/-,p53-/- triple knock-out lymphoma vs normal
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7607 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human pancreatics tumors vs. normal tissue
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7599 | biostudies-arrayexpress
TranscriptomicsCircadian Enhancers Coordinate Multiple Phases of Rhythmic Gene Transcription In Vivo
Mammalian transcriptomes display complex circadian rhythms with multiple phases of gene expression that cannot be accounted for by current models of the molecular clock.  We have determined the underlying mechanisms by measuring nascent RNA transcription around the clock in mouse liver. Unbiased ex...
ORGANISM(S): Mus musculus 
2015-01-06 | E-GEOD-59460 | biostudies-arrayexpress
ModelsThiele2011 - Genome-scale metabolic network of Salmonella Typhimurium (STM_v1_0)
Thiele2011 - Genome-scale metabolic network of Salmonella Typhimurium (STM_v1_0) This model is described in the article: A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2. Thiele I, Hyduke DR, Steeb B, Fankam ...
2015-07-30 | MODEL1507180017 | BioModels
UnknownPARP-1 regulates DNA repair factor availability
Not available
S-SCDT-EMM-2017-08816 | biostudies-other
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