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Proteomics[HPP-2.0] Phosphoproteome Profiling of uEV Reveals p-AQP2 and p-GSK3β as Potential Markers for Diabetic Nephropathy
We used ultra-high-sensitivity quantitative phosphoproteomics to identify phosphoproteins in urinary extracellular vesicles (uEVs) as potential biomarkers of DN. We detected 233 phosphopeptides within the uEVs, with 47 phosphoproteins exhibiting significant alterations in patients with DN compared t...
ORGANISM(S): Homo Sapiens 
2024-02-01 | PXD049107 |
Proteomics[HPP-2.0] Phosphoproteome Profiling of uEV Reveals p-AQP2 and p-GSK3β as Potential Markers for Diabetic Nephropathy-2
We used ultra-high-sensitivity quantitative phosphoproteomics to identify phosphoproteins in urinary extracellular vesicles (uEVs) as potential biomarkers of DN. We detected 233 phosphopeptides within the uEVs, with 47 phosphoproteins exhibiting significant alterations in patients with DN compared t...
ORGANISM(S): Homo Sapiens Bos Taurus 
2024-02-20 | PXD049714 |
ProteomicsProteogenomic Characterization of Skull-base Chordoma
Skull-base chordoma (SBC) is a rare, aggressive bone cancer with a high recurrent rate. Genomic studies of SBC have improved our understanding of the disease’s biology. However, the molecular biological characteristics and the effective therapy of SBC remain unknown. Here, we carried out an integrat...
ORGANISM(S): Homo Sapiens 
2024-07-01 | PXD053550 |
ProteomicsSubcommissural organ (SCO) contributes to brain development via SCO-secreted peptides
To explore the role of SCO and its functional mechanism, we measure the SCO-derived peptide in CSF from C57B/6 mice and SCO-ablated mice.
ORGANISM(S): Mus Musculus 
2025-02-04 | PXD040641 |
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