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MetabolomicsGluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei
Bloodstream form African trypanosomes are thought to rely exclusively upon glycolysis, using glucose as a substrate, for ATP production. Indeed, the pathway has long been considered a potential therapeutic target to tackle the devastating and neglected tropical diseases caused by these parasites. Ho...
2018-12-10 | MTBLS706 | MetaboLights
ProteomicsDegradation of Quaternary amine in methanogen
Elucidation of quaternary amine degradation pathway in the methanogen Methanolobus vulcani B1d
ORGANISM(S): Methanolobus Vulcani (ncbitaxon:38026) 
2019-06-26 | MSV000084013 | MassIVE
UnknownFactors associated with D-dimer levels in HIV-infected individuals.
Not available
S-EPMC3953205 | biostudies-literature
UnknownAssociation of the vitamin D metabolism gene CYP24A1 with coronary artery calcification.
Not available
S-EPMC2988112 | biostudies-literature
MetabolomicsCell-based and multi-omics profiling reveal dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei

Mitochondrial metabolic remodeling is a hallmark of the Trypanosoma brucei digenetic life cycle since the insect stage utilizes the cost-effective oxidative phosphorylation to generate ATP, while bloodstream cells switch to less energetically efficient aerobic glycolysis. Due to difficulties in a...

2020-08-20 | MTBLS1390 | MetaboLights
UnknownAutophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration.
Not available
S-EPMC5173283 | biostudies-literature
UnknownParkinson Symptom Severity and Use of Nutraceuticals.
Not available
S-EPMC9966010 | biostudies-literature
UnknownInhibiting autophagy reduces retinal degeneration caused by protein misfolding.
Not available
S-EPMC6103695 | biostudies-literature
UnknownIdentification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway.
Not available
S-EPMC3184134 | biostudies-literature
UnknownCarbamate and N-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors.
Not available
S-EPMC7957919 | biostudies-literature
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