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TranscriptomicsTranscription profiling of human colorectal cancer samples with CpG island methylator phenotype (CIMP)
The CpG island methylator phenotype (CIMP) in colorectal tumors can be recognized by an increased frequency of aberrant methylation in a specific set of genomic loci. Because of the strong association of CIMP with high microsatellite instability (MSI-H), the identification of CIMP+ tumors within mi...
ORGANISM(S): Homo sapiens 
2008-01-01 | E-TABM-328 | biostudies-arrayexpress
TranscriptomicsEFV-miRNA
Background: LINE-1 elements make up the most abundant retrotransposon family in the human genome. Full-length LINE-1 elements encode their own reverse transcriptase (RT). They are expressed at low levels in normal cells and abundantly in cancer cells. RT down-regulation, by either RNA interference t...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-MTAB-1737 | biostudies-arrayexpress
TranscriptomicsEFV-GE
Background: LINE-1 elements make up the most abundant retrotransposon family in the human genome. Full-length LINE-1 elements encode their own reverse transcriptase (RT). They are expressed at low levels in normal cells and abundantly in cancer cells. RT down-regulation, by either RNA interference t...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-MTAB-1735 | biostudies-arrayexpress
TranscriptomicsEFV-UCR
Background: LINE-1 elements make up the most abundant retrotransposon family in the human genome. Full-length LINE-1 elements encode their own reverse transcriptase (RT). They are expressed at low levels in normal cells and abundantly in cancer cells. RT down-regulation, by either RNA interference t...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-MTAB-1736 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human colorectal cancer samples with high microsatellite instability
Background. Colorectal cancer develops through two main genetic instability pathways characterized by distinct pathologic features and clinical outcome. Results. We investigated colon cancer samples (23 characterized by microsatellite stability, MSS, and 16 by high microsatellite instability, MSI-H)...
ORGANISM(S): Homo sapiens 
2007-09-07 | E-TABM-326 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling by array of human blood monocytes treated with Resveratrol
The effects of resveratrol on human blood monocytes were analyzed on miRNA microarrays
ORGANISM(S): Homo sapiens 
2010-07-20 | E-TABM-1035 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of human acute myeloid leukaemia Kasumi-1 cell line CD34+38- compartment.
The t(8;21) Acute Myeloid Leukaemia (AML) Kasumi-1cell line with N822K KIT mutation, is a model system for leukemogenesis. As AML initiating cells reside in the CD34+CD38- fraction, we addressed the refined cytogenomic characterization and miRNA expression of Kasumi-1 cell line and its FACS-sorted...
ORGANISM(S): Homo sapiens 
2010-02-19 | E-TABM-909 | biostudies-arrayexpress
TranscriptomicsEwing's sarcoma miRNA expression
MicroRNA profile of 34 EWS by microarray
ORGANISM(S): Homo sapiens 
2011-06-15 | E-TABM-1100 | biostudies-arrayexpress
Transcriptomics217CLL
In this study we compared the miRNA expression profile of 217 CLL cases versus various normal B cell subpopulations in the attempt of finding the normal cell subset most similar to CLL cells and gain information on possible miRNA deregulations. Our analyses indicated that CLL cells exhibited a miRNA...
ORGANISM(S): Homo sapiens 
2014-03-01 | E-MTAB-1454 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human cancer samples identifies ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas.
A critical question in molecular oncology is how extensive is the involvement of non-codingRNAs (ncRNAs) in human tumorigenesis. Herein, we report that a large fraction of genomic ultraconserved regions (UCRs) are encoding a particular set of ncRNAs and are altered in human cancers. We show that UCR...
ORGANISM(S): Homo sapiens 
2007-12-01 | E-TABM-184 | biostudies-arrayexpress
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