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TranscriptomicsOverexpression of four and a half LIM domains protein 2 promotes epithelial-mesenchymal transition-like phenotype in fish pre-osteoblasts
Four and a half LIM domains protein 2 (FHL2) is a co-regulator of gene transcription relevant for many signalling pathways and physiological processes. In this work, the role of FHL2 in cell differentiation has been investigated during in vitro mineralization using a Sparus aurata pre-osteoblast cel...
ORGANISM(S): Sparus aurata 
2013-01-03 | E-GEOD-32501 | biostudies-arrayexpress
TranscriptomicsReplenishing co-downregulated miR-100-5p and miR-125b-5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption.
Illumina bead array data from TCam2, 1411H, and 2102Ep cell lines for mRNA expression. Cell lines were treated with either mismatch negative control (MNC) or combination miRNA replenishment with equimolar concentration of miR-100-5p and miR-125b-5p. Five comparisons are provided; namely TCam2 cell l...
ORGANISM(S): Homo sapiens 
2024-03-01 | E-MTAB-13464 | biostudies-arrayexpress
TranscriptomicsTesticular germ cell tumour cells release microRNA containing extracellular vesicles that induce phenotypic and genotypic changes in cells of the tumour microenvironment
Malignant germ-cell-tumours (GCTs) are characterised by microRNA (miRNA/miR-) dysregulation, with universal over-expression of miR-371~373 and miR-302/367 clusters regardless of patient age, tumour site, or subtype (seminoma/yolk-sac-tumour/embryonal carcinoma). These miRNAs are released into the bl...
ORGANISM(S): Homo sapiens 
2023-09-30 | E-MTAB-13322 | biostudies-arrayexpress
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