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ProteomicsEvaluation of the impact of the dietary inclusion of salty and sugary former food products on the liver and plasma profile of pigs through OMICS approaches
The research on alternative and sustainable feed ingredients is a challenge to reduce feed-food competition between humans and monogastrics, in particular pigs. Former food products (FFPs) drop out from the industrial production of food such as pasta, bread, snacks, and chips. They have a high nutri...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-10-17 | PXD049972 | Pride
Former food products Peptidomics Plasma Proteomics Pigs Liver 
ProteomicsEXPLORING THE ANTI-INFLAMMATORY POTENTIAL OF THINNED APPLE POLYPHENOLS: MECHANISTIC PROTEOMICS INSIGHTS INTO DNBS-INDUCED COLITIS MODEL IN MICE
Ulcerative colitis (UC) is a multifactorial inflammatory bowel disease (IBD) with increasing incidence worldwide. Current treatments, such as NSAIDs and corticosteroids, provide partial symptom relief but are associated to significant side effects. This highlights the need for novel therapies with f...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD056914 | Pride
Nf-κb  nrf2  anti-inflammatory  anti-oxidant  polyphenols  proteomics  thinned apples 
ProteomicsThe Carnosine–HNE Michael Adduct as a Redox-Active Species Associated with Nrf2-Dependent Antioxidant and An-ti-Inflammatory Responses
Carnosine (CAR), an endogenous histidine-containing dipeptide, exhibits antioxidant and anti-inflammatory activity in various experimental models; however, its molecular mechanism of action remains poorly understood. Here, we demonstrate that the Michael adduct between CAR and 4-hydroxy-2-nonenal (H...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-06 | PXD075159 | Pride
Carnosine  4-hydroxy-2-nonenal (hne)  nrf2 activation  nf-κb  anti-inflammatory  anti-oxidant. 
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