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UnknownChildren's oral health-related behaviours and early childhood caries: A latent class analysis.

Objective

In this cross-sectional study in a large community-based sample of preschool-age children, we sought to identify distinct clusters of modifiable early childhood oral health-related behaviours (OHBs) and quantify their association with clinical and parent-reported measures of early ...
S-EPMC8589886 | biostudies-literature
UnknownThe parasite intraerythrocytic cycle and human circadian cycle are coupled during malaria infection.
During infections with the malaria parasites Plasmodium vivax, patients exhibit rhythmic fevers every 48 h. These fever cycles correspond with the time the parasites take to traverse the intraerythrocytic cycle (IEC). In other Plasmodium species that infect either humans or mice, the I...
S-EPMC10268210 | biostudies-literature
UnknownColonization and Internalization of Salmonella enterica and Its Prevalence in Cucumber Plants.
Consumption of cucumbers (Cucumis sativus var. sativus) has been linked to several foodborne outbreaks involving Salmonella enterica. The purpose of this work was to investigate the efficiency of colonization and internalization of S. enterica into cucumber plants by vari...
S-EPMC7273826 | biostudies-literature
ProteomicsNebulized and intravenous enzyme replacement therapy in mice with mucopolysaccharidosis type II
Mucopolysaccharidosis Type II is a hereditary lysosomal storage disease characterized by deficiency in the enzyme iduronate 2-sulfatase (IDS). IDS is critical in the breakdown of sulfated glycosaminoglycans and its deficiency leads to an accumulation of these compounds across various tissue types re...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-09 | PXD054411 | Pride
Enzyme replacement therapy Mpsii 
UnknownGlutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activation.
Despite the characteristic etiologies and phenotypes, different brain disorders rely on common pathogenic events. Glutamate-induced neurotoxicity is a pathogenic event shared by different brain disorders. Another event occurring in different brain pathological conditions is the increase of the extra...
S-EPMC5833818 | biostudies-literature
UnknownA Randomized Open-Label Study of Relugolix Alone or Relugolix Combination Therapy in Premenopausal Women.

Background and objective

Relugolix is a gonadotropin-releasing hormone receptor antagonist. Relugolix 40-mg monotherapy is associated with vasomotor symptoms and long-term bone mineral density loss due to hypoestrogenism. This study assessed whether the addition of estradiol (E2) 1 mg and no...
S-EPMC10386916 | biostudies-literature
UnknownRespiratory pathology in the mdx/utrn -/- mouse: A murine model for Duchenne Muscular Dystrophy (DMD).
Duchenne muscular dystrophy (DMD) is an X-linked devastating disease caused by a lack of dystrophin which results in progressive muscle weakness. As muscle weakness progresses, respiratory insufficiency and hypoventilation result in significant morbidity and mortality. The most studied DMD mouse mod...
S-EPMC11805407 | biostudies-literature
UnknownPhysiological and molecular responses to high-temperature stress at anthesis in Brazilian flooded rice.
High-temperature events are projected to increase in frequency under future climate scenarios, threatening rice yields globally. This study investigated the physiological and molecular responses of two Brazilian flooded rice varieties, IRGA 428 and BR-IRGA 409, during the anthesis stage under high-t...
S-EPMC12449062 | biostudies-literature
UnknownNanostructured Lipid Carrier Co-loaded with Doxorubicin and Docosahexaenoic Acid as a Theranostic Agent: Evaluation of Biodistribution and Antitumor Activity in Experimental Model.

Purpose

Nanotheranostic platforms, i.e., the combination of both therapeutic and diagnostic agents on a single platform, are emerging as an interesting tool for the personalized cancer medicine. Therefore, the aim of this work was to evaluate the in vivo properties of a Tc-99m-labeled nanost...
S-EPMC6522249 | biostudies-literature
UnknownClinical application of a scale to assess genomic healthcare empowerment (GEmS): Process and illustrative case examples.
The Genome Empowerment Scale (GEmS), developed as a research tool, assesses perspectives of parents of children with undiagnosed disorders about to undergo exome or genome sequencing related to the process of empowerment. We defined genomic healthcare empowerment as follows: perceived ability to und...
S-EPMC8664895 | biostudies-literature
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