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UnknownStructural control and depth clustering of extensive hydrothermal venting on the shelf of Milos Island.
High-resolution geophysical surveys, complemented by chemical, physical, and visual data collected via the ROV MARUM-SQUID, revealed a previously undocumented intermediate-depth hydrothermal vent field (30-230 m) on the shelf of Milos Island, Greece. Three primary vent areas-Aghia Kiriaki, Paleochor...
S-EPMC12660848 | biostudies-literature
MetabolomicsMetabolomics Insights in Early Childhood Caries
Dental caries is characterized by a dysbiotic shift at the biofilm-tooth surface interface, yet comprehensive biochemical characterizations of the biofilm are scant. We used metabolomics to identify biochemical features of the supragingival biofilm associated with early childhood caries (ECC) preval...
2021-01-29 | MTBLS2215 | MetaboLights
UnknownHeterozygous variants in MYBPC1 are associated with an expanded neuromuscular phenotype beyond arthrogryposis.
Encoding the slow skeletal muscle isoform of myosin binding protein-C, MYBPC1 is associated with autosomal dominant and recessive forms of arthrogryposis. The authors describe a novel association for MYBPC1 in four patients from three independent families with skeletal muscle weakness, myogenic trem...
S-EPMC6688907 | biostudies-literature
UnknownValidation of the Oxford classification of IgA nephropathy in cohorts with different presentations and treatments.
The Oxford Classification of IgA Nephropathy (IgAN) identified mesangial hypercellularity (M), endocapillary proliferation (E), segmental glomerulosclerosis (S), and tubular atrophy/interstitial fibrosis (T) as independent predictors of outcome. Whether it applies to individuals excluded from the or...
S-EPMC4184028 | biostudies-literature
UnknownGeneral and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants.

Background

Adiposity can be measured using BMI (which is based on weight and height) as well as indices of abdominal adiposity. We examined the association between BMI and waist-to-height ratio (WHtR) within and across populations of different world regions and quantified how well these two ...
S-EPMC7616775 | biostudies-literature
UnknownEffect of BMI on safety of bariatric surgery during the COVID-19 pandemic, procedure choice, and safety protocols - An analysis from the GENEVA Study.

Background

It has been suggested that patients with a Body Mass Index (BMI) of > 60 kg/m2 should be offered expedited Bariatric Surgery (BS) during the Coronavirus Disease-2019 (COVID-19) pandemic. The main objective of this study was to assess the safety of this approach.

Meth...

S-EPMC9174153 | biostudies-literature
UnknownIntravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.

Importance

The efficacy of vitamin C for hospitalized patients with COVID-19 is uncertain.

Objective

To determine whether vitamin C improves outcomes for patients with COVID-19.

Design, setting, and participants

Two prospectively harmonized randomized clinical trials enrolled c...
S-EPMC10600726 | biostudies-literature
UnknownQuantitative MRCP Imaging: Accuracy, Repeatability, Reproducibility, and Cohort-Derived Normative Ranges.

Background

Magnetic resonance cholangiopancreatography (MRCP) is an important tool for noninvasive imaging of biliary disease, however, its assessment is currently subjective, resulting in the need for objective biomarkers.

Purpose

To investigate the accuracy, scan/rescan repeatabilit...
S-EPMC7496952 | biostudies-literature
UnknownPrognostic value of NT-proBNP in patients with primary mitral regurgitation undergoing transcatheter edge-to-edge repair.

Aims

The prognostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients undergoing mitral valve transcatheter edge-to-edge repair (M-TEER) for primary mitral regurgitation (PMR) is unclear. This study assessed the association between NT-proBNP and outcomes and explored...
S-EPMC12803553 | biostudies-literature
UnknownStoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.

Objective

To develop and validate a prediction model (STOMA score) for 1-year stoma-free survival in patients with rectal cancer (RC) with anastomotic leakage (AL).

Background

AL after RC resection often results in a permanent stoma.

Methods

This international retrospective coh...
S-EPMC10549897 | biostudies-literature
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