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TranscriptomicsIn vivo transcriptome of Listeria monocytogenes EGDe
Time course study of the mouse infection by comparing the genomic transcriptional patterns of Listeria monocytogenes EGDe grown under laboratory conditions (exponential growth phase) with that of in vivo-grown bacteria (in mouse spleens) over three days of infection. Time course study of the mouse i...
ORGANISM(S): Listeria monocytogenes EGD-e 
2010-06-25 | E-GEOD-13057 | biostudies-arrayexpress
TranscriptomicsMemory-like CD8 T-cells sustain the immune response to chronic viral infections.
We have discovered a small subpopulation of virus-specific CD8 T-cells that sustains the T-cell response in chronic infections. These cells are defined by - and depend on - the expression of the transcription factor Tcf1 (T cell factor 1) and show key characteristics of central memory cells while ...
ORGANISM(S): Mus musculus 
2016-08-22 | E-GEOD-83978 | biostudies-arrayexpress
ProteomicsFA-SAT ncRNA interactome
FA-SAT is a satellite DNA sequence present and transcribed in many Bilateria species, what may anticipate a conserved and significant function in these genomes. Here we prove that in cat and human cells, FA-SAT satellite transcripts play a nuclear function at the G1 phase of the cell cycle. We ident...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Felis silvestris 
2020-03-19 | PXD010081 | Pride
Fa-sat  satellite dna  non-coding rna  apoptosis  interactome  swath-ms 
TranscriptomicsRNA-seq of whole blood samples from patients with visceral leishmaniasis.
To ascertain which molecular pathways underlying the pathogenesis of human visceral leishmaniasis (VL) caused by the protozoan parasite Leishmania infantum, we performed modular co-expression gene networks analysis using CEMiTool R package and the transcriptional profile of whole blood samples from ...
ORGANISM(S): Homo sapiens 
2018-01-25 | E-MTAB-6137 | biostudies-arrayexpress
TranscriptomicsDownregulation of specific miRNAs in hyperdiploid multiple myeloma mimics the oncogenic effect of IgH translocations occurring in the non-hyperdiploid subtype
Currently, multiple myeloma (MM) patients are broadly grouped into a non-hyperdiploid Group (nh-MM), highly enriched for IgH translocations, or into a hyperdiploid Group (h-MM), which is typically characterized by trisomies of some odd-numbered chromosomes. We compared the miRNA expression profiles...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-40308 | biostudies-arrayexpress
MetabolomicsMesenchymal stromal cells secretome restores bioenergetic and redox homeostasis in human proximal tubule cells after ischemic injury

BACKGROUND: Ischemia/reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI). The current standard of care focuses on supporting kidney function, stating the need for more efficient and targeted therapies to enhance repair. Mesenchymal Stromal Cells (MSCs) and ...

2023-10-16 | MTBLS6279 | MetaboLights
TranscriptomicsNeuraminidase-exposed galactose promotes Streptococcus pneumoniae biofilm formation during colonization
Galactose promotes pneumococcal biofilms in vivo 15 mRNA profiles of Streptococcus pneumoniae samples that were grown under different conditions were generated using deep sequencing.
ORGANISM(S): Streptococcus pneumoniae 
2016-08-04 | E-GEOD-85196 | biostudies-arrayexpress
MetabolomicsGeographic variation of mutagenic exposures in kidney cancer genomes

International differences in the incidence of many cancer types indicate the existence of carcinogen exposures that have not been identified by conventional epidemiology yet potentially make a substantial contribution to cancer burden1. This pertains to clear cell renal cell carcinoma (ccRCC), fo...

2024-03-26 | MTBLS9394 | MetaboLights
UnknownEvaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries.
Not available
S-EPMC10771257 | biostudies-literature
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