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GenomicsNLRC5 specifically transactivates MHC class I and related genes through a distinctive SXY module
MHC class II (MHCII) genes are transactivated by the NOD-like receptor (NLR) factor CIITA, which is recruited to SXY regulatory modules of MHC promoters via a DNA-binding “enhanceosome” complex. NLRC5, another NLR protein, was recently found to control transcription of MHC class I (MHCI) genes. Howe...
ORGANISM(S): Mus musculus 
2015-02-27 | E-GEOD-59092 | biostudies-arrayexpress
TranscriptomicsDifferentially regulated genes in control and c-myc N-myc deficient LT-HSCs
Analysis of HSCs from control and c-myc N-myc deficient long-term hematopoietic stem cells. HSCs lacking both c-myc and N-myc display increased apoptosis rates. Data provide insight into the molecular changes occuring upon complete loss of Myc activity, clarifying the resulting apoptotic mechanism a...
ORGANISM(S): Mus musculus 
2009-02-20 | E-GEOD-12467 | biostudies-arrayexpress
UnknownData-driven flow cytometry classification of blast differentiation in older patients with acute myeloid leukemia.
Not available
S-EPMC12082131 | biostudies-literature
UnknownLong-term effectiveness and tolerability of dolutegravir/lamivudine in treatment-naive people with HIV: an analysis of a multicentre cohort at 96 weeks.
Not available
S-EPMC11879157 | biostudies-literature
UnknownLoss of humoral response 3 months after SARS-CoV-2 vaccination in the CKD spectrum: the multicentric SENCOVAC study.
Not available
S-EPMC9383183 | biostudies-literature
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