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TranscriptomicsExpression data from immortalized and transformed WT and HGPS cell lines
Primary skin fibroblasts from HGPS patients and an age-matched control wild-type individuals were challenged in a standard transformation assay by retroviral introduction of TERT (T), V12-HRAS (R) and SV40 large and small T antigens (S). TERT-Immortalized cell lines from the same sources were also g...
ORGANISM(S): Homo sapiens 
2014-10-02 | E-GEOD-60518 | biostudies-arrayexpress
TranscriptomicsExpression data from transformed WT and HGPS cell lines, including HGPS cells after knock-down of BRD4
Primary skin fibroblasts from a HGPS patient and an age-matched control wild-type individual were challenged in a standard transformation assay by retroviral introduction of TERT (T), V12-HRAS (R) and SV40 large and small T antigens (S). Knock-down of BRD4 in this TRS-HGPS cell line (TRS-HGPS-shBRD4...
ORGANISM(S): Homo sapiens 
2014-10-02 | E-GEOD-60519 | biostudies-arrayexpress
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