To investigate the function of ferroportin, we deleted ferroportin gene in mouse placenta using cre. We performed RNA-sequencing on six ferroportin knockout and four control placentas.
Background: Host iron deficiency is protective against severe malaria as the human malaria parasite Plasmodium falciparum depends on free iron from its host to proliferate. Due to the absence of transferrin, ferritin, ferroportin, and a functional heme oxygenase, the parasite’s essential pathways of...
