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TranscriptomicsGene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma
Aberrant activation of signaling pathways controlled in normal epithelial cells by the epidermal growth factor receptor (EGFR) has been linked to cetuximab (a monoclonal antibody against EGFR) resistance in head and neck squamous cell carcinoma (HNSCC). To infer relevant and specific pathway activat...
ORGANISM(S): Homo sapiens 
2012-05-22 | E-GEOD-32975 | biostudies-arrayexpress
TranscriptomicsA 3'-UTR KRAS-variant is associated with cisplatin resistance in patients with recurrent and/or metastatic head and neck squamous cell carcinoma.
To determine the differential expression of KRAS-variant HNSCC (head and neck squamous cell carcinoma) cell lines. Total RNA collected from a panel of HNSCC cell lines.
ORGANISM(S): Homo sapiens 
2014-10-02 | E-GEOD-36110 | biostudies-arrayexpress
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