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TranscriptomicsMolecular and transcriptional characterization of chromosome 17p loss in chronic lymphocytic leukemia, experiment A
Distinct genetic abnormalities such as TP53 deletion at 17p13.1, have been identified as having an adverse prognostic relevance in B-cell chronic lymphocytic leukemia (B-CLL). Conventional cytogenetic studies have shown that TP53 deletion in B-CLL is associated predominantly with 17p loss resulting ...
ORGANISM(S): Homo sapiens 
2008-11-11 | E-GEOD-9992 | biostudies-arrayexpress
TranscriptomicsMolecular and transcriptional characterization of chromosome 17p loss in chronic lymphocytic leukemia, experiment B
Distinct genetic abnormalities such as TP53 deletion at 17p13.1, have been identified as having an adverse prognostic relevance in B-cell chronic lymphocytic leukemia (B-CLL). Conventional cytogenetic studies have shown that TP53 deletion in B-CLL is associated predominantly with 17p loss resulting ...
ORGANISM(S): Homo sapiens 
2008-11-11 | E-GEOD-11036 | biostudies-arrayexpress
TranscriptomicsRelevance of Chromosome 2p Gain in Early Binet Stage A Chronic Lymphocytic Leukemia (expression)
Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease characterized by chromosomal aberrations of prognostic significance. Recent studies showed that gain of chromosome 2p is a recurrent lesion in CLL. We investigated the 2p gain and its relationship with prognostic biomarkers in ...
ORGANISM(S): Homo sapiens 
2012-10-12 | E-GEOD-38611 | biostudies-arrayexpress
TranscriptomicsRelevance of Chromosome 2p Gain in Early Binet Stage A Chronic Lymphocytic Leukemia (SNP)
Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease characterized by chromosomal aberrations of prognostic significance. Recent studies showed that gain of chromosome 2p is a recurrent lesion in CLL. We investigated the 2p gain and its relationship with prognostic biomarkers in ...
ORGANISM(S): Homo sapiens 
2012-10-12 | E-GEOD-38613 | biostudies-arrayexpress
TranscriptomicsGenomic approach in B-cell Chronic Lymphocytic Leukemia: molecularly distinct subgroups of patients with 13q14 deletion
B-cell chronic lymphocytic leukemia (B-CLL) is characterized by a highly variable clinical course that reflects its heterogeneous genomic pattern. To better define molecular subtypes of the disease, we performed SNP and gene expression profiling microarray analyses in a panel of early stage (Binet A...
ORGANISM(S): Homo sapiens 
2010-09-01 | E-GEOD-16746 | biostudies-arrayexpress
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