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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
MetabolomicsJ-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis
1H nuclear magnetic resonance (NMR) spectroscopy-based metabolic phenotyping is now widely used for large-scale epidemiological applications. To minimize signal overlap present in 1D 1H NMR spectra, we have investigated the use of 2D J-resolved (JRES) 1H NMR spectroscopy for large-scale phenotyping ...
2018-07-23 | MTBLS540 | MetaboLights
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
UnknownExpression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung.
Not available
S-EPMC4874209 | biostudies-literature
UnknownBaseline prevalence of molecular marker of sulfadoxine/pyrimethamine resistance in Ebonyi and Osun states, Nigeria: amplicon deep sequencing of dhps-540.
Not available
S-EPMC9978573 | biostudies-literature
UnknownEnhanced ion acceleration from transparency-driven foils demonstrated at two ultraintense laser facilities.
Not available
S-EPMC10011581 | biostudies-literature
GenomicsCPCG_Het_Study - samples
Aligned Sequence (bam format), Duplicates removed
EGAD00001001329 | EGA
GenomicsCPCG Het Study, Raw Fastq Sequence - samples
Raw sequence data, fastq format
EGAD00001002885 | EGA
GenomicsCPC-GENE Prostate Cancer Heterogeneity Study
Herein we describe a molecular portrait of potentially curable, Gleason 7 and intermediate risk prostate cancer based on genome-wide CNV profiles of 96 patients, and subsequent whole-genome sequencing of 28 tumours from 10 patients, using DNA quantities that are achievable in diagnostic biopsies (50...
EGAS00001000549 | EGA
UnknownTissue-specific genotype-phenotype correlations among USH2A-related disorders in the RUSH2A study.
Not available
S-EPMC9018588 | biostudies-literature
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