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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
MetabolomicsJ-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis
1H nuclear magnetic resonance (NMR) spectroscopy-based metabolic phenotyping is now widely used for large-scale epidemiological applications. To minimize signal overlap present in 1D 1H NMR spectra, we have investigated the use of 2D J-resolved (JRES) 1H NMR spectroscopy for large-scale phenotyping ...
2018-07-23 | MTBLS540 | MetaboLights
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
UnknownExpression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung.
Not available
S-EPMC4874209 | biostudies-literature
UnknownBaseline prevalence of molecular marker of sulfadoxine/pyrimethamine resistance in Ebonyi and Osun states, Nigeria: amplicon deep sequencing of dhps-540.
Not available
S-EPMC9978573 | biostudies-literature
UnknownEnhanced ion acceleration from transparency-driven foils demonstrated at two ultraintense laser facilities.
Not available
S-EPMC10011581 | biostudies-literature
ProteomicsIFN-γ-driven iNOS induction in macrophages mediates CAR T cell resistance in B cell lymphoma
Chimeric antigen receptor (CAR) T cell therapies have revolutionized B cell malignancy treatment, but subsets of patients with large B cell lymphoma (LBCL) experience primary resistance or relapse after CAR T cell treatment. To uncover tumor microenvironment (TME)-induced resistance mechanisms, we e...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-30 | PXD079073 | Pride
Macrophages B cell lymphoma Interferon Inos Chimeric antigen receptor t cell 
ProteomicsIFN-γ-driven iNOS induction in macrophages mediates CAR T cell resistance in B cell lymphoma: Phosphoproteomics
Chimeric antigen receptor (CAR) T cell therapies have revolutionized B cell malignancy treatment, but subsets of patients with large B cell lymphoma (LBCL) experience primary resistance or relapse after CAR T cell treatment. To uncover tumor microenvironment (TME)-induced resistance mechanisms, we e...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-30 | PXD079082 | Pride
Macrophages B cell lymphoma Interferon Inos Chimeric antigen receptor t cell 
GenomicsCPCG_Het_Study - samples
Aligned Sequence (bam format), Duplicates removed
EGAD00001001329 | EGA
GenomicsCPCG Het Study, Raw Fastq Sequence - samples
Raw sequence data, fastq format
EGAD00001002885 | EGA
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