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ProteomicsAre These Cardiomyocytes? Protocol Development Reveals Impact of Sample Preparation on the Accuracy of Identifying Cardiomyocytes by Flow Cytometry
Several protocols now support efficient differentiation of human pluripotent stem cells to cardiomyocytes (hPSC-CMs) but these still indicate line-to-line variability. As the number of studies implementing this technology expands, accurate assessment of cell identity is paramount to well-defined stu...
ORGANISM(S): Homo Sapiens 
PXD014971 | panorama
GenomicsWhole-genome nucleosome mapping in meiotic diploid S. cerevisiae
We determined nucleosome positions throughout the genome in diploid S. cerevisiae undergoing early stages of synchronous meiosis. This study sought to assess if systematic reorganization of nucleosomes occurs during meiotic prophase at or near sites of DNA double strand break formation. Six samples ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-07 | E-GEOD-26452 | biostudies-arrayexpress
TranscriptomicsGenetic and molecular basis of drug resistance and species-specific drug action in Schistosome parasites
Oxamniquine resistance evolved in the human blood fluke (Schistosoma mansoni) in Brazil in the 1970s. We crossed parental parasites differing ~500-fold in drug response, determined drug sensitivity and marker segregation in clonally-derived F2s, and identified a single QTL (LOD=31) on chromosome 6. ...
ORGANISM(S): Schistosoma mansoni 
2013-12-05 | E-GEOD-51847 | biostudies-arrayexpress
UnknownMixing and flow-induced nanoprecipitation for morphology control of silk fibroin self-assembly.
Not available
S-EPMC8982335 | biostudies-literature
ProteomicsA Clinical trial ready proteomics workflow to support large-scale analysis of Human Plasma: application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial
Background: Proteomic mass spectrometry is widely used to quantify proteins in biological specimens for biomarker discovery. Clinical studies requiring proteomic analysis of plasma are more complicated due to the high dynamic range and abundance of major plasma proteins. There is an unmet need to de...
ORGANISM(S): Homo sapiens (Human) 
2023-09-29 | PXD029732 | Pride
Plasma Dia Clinical trial Clionical proteomics Orbitrap 
TranscriptomicsGlobal discovery and characterization of small non-coding RNAs in marine microalgae
Background: Marine phytoplankton are responsible for 50% of the CO2 that is fixed annually worldwide and contribute massively to other biogeochemical cycles in the oceans. Diatoms and coccolithophores play a significant role as the base of the marine food web and they sequester carbon due to their a...
ORGANISM(S): Thalassiosira pseudonana CCMP1335 
2015-03-06 | E-GEOD-57987 | biostudies-arrayexpress
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
ModelsPeterson2010 - Integrated calcium homeostasis and bone remodelling
Peterson2010 - integrated calcium homeostasis and bone remodelling This model is described in the article: A physiologically based mathematical model of integrated calcium homeostasis and bone remodeling. Peterson MC, Riggs MM. Bone 2010 Jan; 46(1): 49-63 Abstract: ...
2024-09-02 | BIOMD0000000613 | BioModels
ProteomicsPacific Ocean metaproteomics, METZYME KM1128
Global metaproteomic analyses of microbial biomass from the upper water column of the Central Pacific Ocean. This dataset was used as a discovery dataset to identify peptide biomarkers for cyanobacterial populations for use in targeted metaproteomic calibrated multiple reaction monitoring (MRM) anal...
ORGANISM(S): Environmental Samples (ncbitaxon:318178) 
2021-11-05 | MSV000088323 | MassIVE
MetabolomicsMaHPIC Experiment HuC - Metabolomics of plasma samples from human volunteers infected with Plasmodium vivax
Project Description:
The Malaria Host-Pathogen Interaction Center (MaHPIC) is a transdisciplinary malaria systems biology research program initially supported by an NIH/NIAID contract (HHSN272201200031C, 2012-2017; see http://w...
2018-06-19 | MTBLS665 | MetaboLights
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