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TranscriptomicsscRNA-seq analysis of cell subpopulations of the bronchoalveolar lavage fluid of healthy dogs
In dogs, a species for which markers of cell populations are often limiting, we sought to evaluate in an unbiased way the heterogeneity of cell subpopulations in the bronchoalveolar lavage fluid of healthy dogs, by single-cell RNA-sequencing.
ORGANISM(S): Canis lupus familiaris 
2020-06-29 | E-MTAB-9265 | biostudies-arrayexpress
TranscriptomicsscRNA-seq analysis of cell subpopulations of the healthy canine lung
We used the scRNA-seq to establish a comprehensive molecular cell atlas of the healthy canine lung, expanding our knowledge of lung cell subpopulations in dogs, and providing the molecular foundation for investigating lung cell identities and functions in lung diseases across species.
ORGANISM(S): Canis lupus familiaris 
2025-02-27 | E-MTAB-14296 | biostudies-arrayexpress
TranscriptomicsIdentification of pro-fibrotic macrophages populations by scRNA-seq in West Highland white terriers affected with canine idiopathic pulmonary fibrosis
We used the scRNA-seq to characterize disease-related heterogeneity within cell populations of macrophages/monocytes in the bronchoalveolar lavage fluid from West Highland white terriers either healthy or affected with canine idioapthic pulmonary fibrosis. The disease is still not well understood, o...
ORGANISM(S): Canis lupus familiaris 
2020-12-02 | E-MTAB-9623 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of lung monocytes and macrophages in mice
We developed a simplified flow cytometry strategy in order to discriminate monocytes and macrophages in the lung of C57BL/6 mice. Using this strategy, we identified autofluorescent F4/80+ CD11c+ alveolar macrophages, non-autofluorescent CD64+Ly-6C- interstitial macrophages and Ly-6Chi monocytes resi...
ORGANISM(S): Mus musculus 
2017-03-01 | E-MTAB-5012 | biostudies-arrayexpress
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