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TranscriptomicsEvaluation of the robustness of classification of carcinogen-modified transcriptomic responses in HepaRG cells and the interlaboratory reproducibility of the model
Efforts to develop alternatives which can at least partially replace some of the currently used in vivo tests are ongoing. The recently ended FP6 European project carcinoGENOMICS had the goal to use the combination of toxicogenomics and in vitro cell culture models for identification of genotoxic- a...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-48990 | biostudies-arrayexpress
TranscriptomicsOverexpression of miR-155 enhances B-cell lymphoma growth by targeting TBRG1
MYC regulates the expression of multiple microRNA (miRNA) genes and defines the Burkitt lymphoma (BL) miRNA signature. Here, we investigate the role of the MYC-regulated miRNAs by gain- and loss-of-function analysis. Overexpression of 5 miRNAs that were significantly downregulated by MYC resulted in...
ORGANISM(S): Homo sapiens 
2015-02-20 | E-GEOD-64484 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of Arabidopsis plants grown under elevated C02 conditions
Plants were grown in liquid media at ambient air composition [0.03% CO2, 78.97% N2, 21% O2] for 12 days. On 13th day one set (“perturbed set”) of samples (20 samples) were exposed to air with elevated CO2 composition [1% CO2, 78% N2, 21% O2] and the other set (“control set”) of samples (20 samples) ...
ORGANISM(S): Arabidopsis thaliana 
2006-08-31 | E-MEXP-773 | biostudies-arrayexpress
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