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Regulatory T cells (Tregs) play crucial role in maintenance of peripheral tolerance. Numerous clinical trials confirmed safety and efficacy of Treg treatment of for deleterious immune responses. However, Tregs lose their characteristic phenotype and suppressive potential during expansion ex vivo. In...
ORGANISM(S): Homo sapiens 
The experimental design demonstrates that zebularine, a DNA methyltransferase inhibitor, promotes regeneration in the mouse and that retinoic acid and zebularine synergistically accelerate this process.
ORGANISM(S): Homo sapiens 
In this experiment we determined the effects of FBS supplementation and subsequent deprivation (after second passage) on the whole transcriptome, including comprehensive mRNA and miRNA profiling.
ORGANISM(S): Homo sapiens 
In this experiment we determined the effects of FBS supplementation and subsequent deprivation (after second passage) on the whole transcriptome, including comprehensive mRNA and miRNA profiling.
ORGANISM(S): Homo sapiens 
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